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GENE：AGO3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AGO3
FullNmae argonaute RISC catalytic component 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18421
EnsembleID ENSG00000126070
Uniprot Q9H9G7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AGO3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AGO3 GO:0000794,GO:0000932,GO:0003723,GO:0003725,GO:0003727,GO:0003727,GO:0004521,GO:0004521,GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006402,GO:0010501,GO:0010501,GO:0010628,GO:0016020,GO:0016442,GO:0031054,GO:0035196,GO:0035198,GO:0035198,GO:0035278,GO:0036464,GO:0046872,GO:0070578,GO:0070922,GO:0072091,GO:0090624,GO:1901224

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 AGO3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 AGO3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 AGO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AGO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AGO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 AGO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AGO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AGO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF AGO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 AGO3 17699775 25416803 mrna cleavage,inhibition array technology TarBase
URS000008F0CF AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C AGO3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 AGO3 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A AGO3 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 AGO3 23446348 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000298BA3 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 AGO3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D AGO3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001D69F6 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000031BC7D AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008C563 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 AGO3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 AGO3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A AGO3 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000251D0B AGO3 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C11BC AGO3 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C0FCB AGO3 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000315338 AGO3 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039607D AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018E72A AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D2F5 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000038446A AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006A1CB AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000057A7C AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CE113 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000027464B AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001DC1D3 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000156390 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 AGO3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC AGO3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000008A99 AGO3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000221168 AGO3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 AGO3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CC20C AGO3 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 AGO3 25348397 N/A physical interaction ComPPI
TRIM21 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLNS1A AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTB AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HSP90AB1 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL3 AGO3 25348397 N/A physical interaction ComPPI
PRKAR1A AGO3 25348397 N/A physical interaction ComPPI
UBC AGO3 25348397 N/A physical interaction ComPPI
HSP90AA1 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TARBP2 AGO3 25348397 N/A physical interaction ComPPI
EEF1A1 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRMT5 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPTAN1 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK38 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBM10 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
XPO1 AGO3 25348397 N/A physical interaction ComPPI
IPO8 AGO3 19167051 24234451 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,cosedimentation through density gradient,pull down,physical interaction,confocal microscopy ComPPI,IntAct
WDR77 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPTBN1 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1A AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHB2 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAP1LC3A AGO3 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4B AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA9 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AP3D1 AGO3 25348397 N/A physical interaction ComPPI
CAND1 AGO3 25348397 N/A physical interaction ComPPI
AP3B1 AGO3 25348397 N/A physical interaction ComPPI
EIF4B AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP5C AGO3 24234451 25348397 28330616 association,physical association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
TUBB4A AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CIR1 AGO3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BDNF AGO3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RANGRF AGO3 25348397 N/A physical interaction ComPPI
BRCA1 AGO3 25348397 N/A physical interaction ComPPI
AP3S1 AGO3 25348397 N/A physical interaction ComPPI
TOMM20 AGO3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EIF3L AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJA1 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AGO2 AGO3 17932509 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AGO1 AGO3 25348397 N/A physical interaction ComPPI
DICER1 AGO3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RUVBL2 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SF3B6 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYH9 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ECH1 AGO3 24234451 25348397 29426014 association anti tag coimmunoprecipitation ComPPI,IntAct
PSPC1 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A3 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ZNF346 AGO3 25348397 N/A physical interaction ComPPI
ATP4B AGO3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TNRC6B AGO3 19167051 24043833 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
ATOH1 AGO3 25348397 N/A physical interaction ComPPI
BCAR1 AGO3 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
CCT3 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OTUD4 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDOST AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DBT AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATAD3B AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUN2 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
QPCTL AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP5 AGO3 25348397 N/A physical interaction ComPPI
TAB1 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPF31 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB2A AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AGO3 EDC4 23064648 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG5 AGO3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B3472 AGO3 27087310 direct interaction,inhibition N/A NPInter

Visualization










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