GENE：CSTF1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CSTF1 |
| FullNmae | cleavage stimulation factor subunit 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2483 |
| EnsembleID | ENSG00000101138 |
| Uniprot | Q05048 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CSTF1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CSTF1 | GO:0003723,GO:0005515,GO:0005654,GO:0005654,GO:0005848,GO:0031124 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CSTF1 | hsa:1477 | path:hsa03015 | mRNA surveillance pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | CSTF1 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | CSTF1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | CSTF1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CSTF1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | CSTF1 | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| SMARCA4 | CSTF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CSTF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CSTF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CSTF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CSTF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000272039 | CSTF1 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS0000016914 | CSTF1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000022AAA | CSTF1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F1B8C | CSTF1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002971AB | CSTF1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000451A1 | CSTF1 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | CSTF1 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003BBF48 | CSTF1 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001BCAC5 | CSTF1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | CSTF1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000209F04 | CSTF1 | 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | CSTF1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | CSTF1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ECFE5 | CSTF1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000184017 | CSTF1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B83FE | CSTF1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C1E1 | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A8BC6 | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032AE90 | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5ECC | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000080D0A | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000058276F | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004E78D3 | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000365675 | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | CSTF1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C7662 | CSTF1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CSTF1 | BARD1 | 25361965 | interaction type | N/A | PTMCode2 |
| BARD1 | CSTF1 | 25361965 | interaction type | N/A | PTMCode2 |
| CSTF1 | CPSF2 | 25361965 | interaction type | N/A | PTMCode2 |
| CPSF2 | CSTF1 | 25361965 | interaction type | N/A | PTMCode2 |
| CSTF1 | CSTF3 | 25361965 | interaction type | N/A | PTMCode2 |
| CSTF3 | CSTF1 | 25361965 | interaction type | N/A | PTMCode2 |
| CSTF1 | BRCA1 | 25361965 | interaction type | N/A | PTMCode2 |
| BRCA1 | CSTF1 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ZBED1 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| GCM2 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| HSPBP1 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| PCNA | CSTF1 | 10477523 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| BMI1 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| DCUN1D1 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| FIP1L1 | CSTF1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RACGAP1 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| MAPK3 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| DLD | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| XPO6 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| NFATC2 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| PAFAH1B1 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| LMO2 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| RRM2 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| CYP1A1 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| GTF2E2 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| YAP1 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| POLR2A | CSTF1 | 11459828 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| TOLLIP | CSTF1 | 21903422 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BARD1 | CSTF1 | 10477523 11257228 14525934 18842000 20379136 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| CSTF2 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF3 | CSTF1 | 10669729 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| CSTF1 | BRCA1 | 11278247 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CSTF1 | USP15 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSTF1 | HNRNPA1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | PARN | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | MPG | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | ASNS | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | NDRG3 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | DNAAF5 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | NMD3 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | NPEPL1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | TARDBP | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | TTC27 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | CPSF3 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSTF1 | UBXN7 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | SNRPN | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | BMP1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | G3BP1 | 25348397 | N/A | physical interaction | ComPPI |
| PLK2 | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| POLR1A | CSTF1 | 10477523 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| CSTF2T | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF1 | CSTF1 | 10669729 14525934 | N/A | experimental interaction detection | HPRD |
| SYMPK | CSTF1 | 10669729 27898060 | stimulant | N/A | OmniPath |
| TOLLIP | CSTF1 | 21903422 27898060 | N/A | N/A | OmniPath |