GENE:INAVA
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | INAVA |
| FullNmae | innate immunity activator |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25599 |
| EnsembleID | ENSG00000163362 |
| Uniprot | Q3KP66 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| INAVA | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| INAVA | GO:0002221,GO:0002720,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0016604,GO:0031398,GO:0031398,GO:0032494,GO:0032495,GO:0032731,GO:0032733,GO:0032755,GO:0032874,GO:0034334,GO:0034334,GO:0043123,GO:0043410,GO:0045087,GO:0060729,GO:0070431,GO:1903409 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | INAVA | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | INAVA | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | INAVA | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | INAVA | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | INAVA | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | INAVA | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | INAVA | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001CC4BD | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B538 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001BCAC5 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027464B | INAVA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DC1D3 | INAVA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | INAVA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000156390 | INAVA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000160683 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TAX1BP3 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| GRN | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| DCTN1 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| CYTH2 | INAVA | 24234451 25348397 29420262 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CYTH1 | INAVA | 24234451 25348397 29420262 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ACTR1A | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| SFN | INAVA | 15778465 24234451 25348397 | physical association | tandem affinity purification | ComPPI,IntAct |
| SMARCA1 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| ARHGEF7 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| TRIM27 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| DCTN2 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| CALCOCO2 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| DCTN3 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| CYTH3 | INAVA | 24234451 25348397 29420262 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DCAF8 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| DCTN6 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
| INAVA | NEDD8 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | RPL6 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | ATAD3A | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | FMR1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | RPS6 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | CUL1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | RPS8 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | FXR1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | BTRC | 24234451 29420262 | association,physical association | anti tag coimmunoprecipitation | IntAct |
| INAVA | RPL3L | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | RPS11 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | TNKS | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | RPL28 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | RPL10 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | RPL18 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | FXR2 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | RBX1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | CALR | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | SKP1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
| INAVA | FBXW11 | 24234451 29420262 | association,physical association | anti tag coimmunoprecipitation | IntAct |
