GENE:INAVA
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | INAVA |
FullNmae | innate immunity activator |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:25599 |
EnsembleID | ENSG00000163362 |
Uniprot | Q3KP66 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
INAVA | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
INAVA | GO:0002221,GO:0002720,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0016604,GO:0031398,GO:0031398,GO:0032494,GO:0032495,GO:0032731,GO:0032733,GO:0032755,GO:0032874,GO:0034334,GO:0034334,GO:0043123,GO:0043410,GO:0045087,GO:0060729,GO:0070431,GO:1903409 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ESR1 | INAVA | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
ETS1 | INAVA | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA3 | INAVA | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
YBX1 | INAVA | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
TFAP2C | INAVA | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
PRDM14 | INAVA | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
VDR | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | INAVA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237AF9 | INAVA | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00001CC4BD | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075B538 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001BCAC5 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000027464B | INAVA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001DC1D3 | INAVA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001FC26E | INAVA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000156390 | INAVA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000160683 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C5969 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003AA845 | INAVA | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TAX1BP3 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
GRN | INAVA | 25348397 | N/A | physical interaction | ComPPI |
CDH1 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
DCTN1 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
CYTH2 | INAVA | 24234451 25348397 29420262 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CYTH1 | INAVA | 24234451 25348397 29420262 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
ACTR1A | INAVA | 25348397 | N/A | physical interaction | ComPPI |
SFN | INAVA | 15778465 24234451 25348397 | physical association | tandem affinity purification | ComPPI,IntAct |
SMARCA1 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
ARHGEF7 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
TRIM27 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
DCTN2 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
CALCOCO2 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
DCTN3 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
CYTH3 | INAVA | 24234451 25348397 29420262 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
DCAF8 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
DCTN6 | INAVA | 25348397 | N/A | physical interaction | ComPPI |
INAVA | NEDD8 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | RPL6 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | ATAD3A | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | FMR1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | RPS6 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | CUL1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | RPS8 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | FXR1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | BTRC | 24234451 29420262 | association,physical association | anti tag coimmunoprecipitation | IntAct |
INAVA | RPL3L | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | RPS11 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | TNKS | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | RPL28 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | RPL10 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | RPL18 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | FXR2 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | RBX1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | CALR | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | SKP1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | FBXW11 | 24234451 29420262 | association,physical association | anti tag coimmunoprecipitation | IntAct |