Gene Information gene info

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GENE：SLF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLF1
FullNmae SMC5-SMC6 complex localization factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25408
EnsembleID ENSG00000133302
Uniprot Q9BQI6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLF1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLF1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLF1 GO:0000724,GO:0000781,GO:0000786,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0006974,GO:0006974,GO:0016925,GO:0030915,GO:0031334,GO:0031625,GO:0032204,GO:0034184,GO:0035861,GO:0035861,GO:0042405,GO:0044877,GO:0140588,GO:1990166,GO:1990166,GO:2000781

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 SLF1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 SLF1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SLF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SLF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SLF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SLF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 SLF1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 SLF1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00005DEC41 SLF1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 SLF1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PARD6B SLF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD18 SLF1 22036607 24234451 25348397 26496610 27898060 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
UBE2A SLF1 25348397 N/A physical interaction ComPPI
NFKB1 SLF1 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
BRCA1 SLF1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
USP21 SLF1 25348397 N/A physical interaction ComPPI
SMC6 SLF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDIA6 SLF1 24234451 30021884 physical association cross-linking study IntAct
SLF1 UBTF 24234451 30021884 physical association cross-linking study IntAct

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