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GENE：PRIM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRIM1
FullNmae DNA primase subunit 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9369
EnsembleID ENSG00000198056
Uniprot P49642

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRIM1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRIM1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRIM1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRIM1 GO:0000287,GO:0003896,GO:0003896,GO:0003896,GO:0005515,GO:0005654,GO:0005658,GO:0005658,GO:0005658,GO:0006269,GO:0006269,GO:0006270,GO:0008270,GO:0016020,GO:0032553

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PRIM1 hsa:5557 path:hsa03030 DNA replication - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
POLA1 PRIM1 15132993 26192618 9115215 interaction type N/A ACSN
PRIM2 PRIM1 15132993 26192618 9115215 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR PRIM1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PRIM1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PRIM1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC PRIM1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 PRIM1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PRIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PRIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PRIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PRIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PRIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 PRIM1 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000171CD1 PRIM1 18362358 rna interference,inhibition array technology miRSponge
URS0000171CD1 PRIM1 18362358 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 PRIM1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00000AA464 PRIM1 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 PRIM1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 PRIM1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000B59A2 PRIM1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 PRIM1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000F4AC3 PRIM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000355E82 PRIM1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A PRIM1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 PRIM1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 PRIM1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C PRIM1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 PRIM1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 PRIM1 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC PRIM1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A PRIM1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 PRIM1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 PRIM1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 PRIM1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000009262D PRIM1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF PRIM1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 PRIM1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB PRIM1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA PRIM1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 PRIM1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A PRIM1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 PRIM1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 PRIM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000237E04 PRIM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B989F PRIM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000078918 PRIM1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRIM1 PRIM2 25361965 interaction type N/A PTMCode2
PRIM2 PRIM1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CIAO1 PRIM1 25348397 N/A physical interaction ComPPI
CIAO2B PRIM1 24234451 25348397 28178521 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LMNA PRIM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STN1 PRIM1 25348397 N/A physical interaction ComPPI
POLA1 PRIM1 12138179 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
XRCC5 PRIM1 25348397 N/A physical interaction ComPPI
RPA1 PRIM1 25348397 N/A physical interaction ComPPI
POLE PRIM1 25348397 N/A physical interaction ComPPI
CHM PRIM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RPA2 PRIM1 25348397 N/A physical interaction ComPPI
RPA3 PRIM1 25348397 N/A physical interaction ComPPI
EGFR PRIM1 25348397 N/A physical interaction ComPPI
CDK7 PRIM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MMS19 PRIM1 24234451 25348397 28178521 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRIM1 MRPL38 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PRIM1 RAE1 25348397 N/A physical interaction ComPPI
PRIM1 COPS6 25348397 N/A physical interaction ComPPI
PRIM1 PRIM2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRIM1 POLA2 12138179 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
PRIM1 MDC1 25348397 N/A physical interaction ComPPI
PRIM1 MOV10 25348397 N/A physical interaction ComPPI
PRIM1 NXF1 25348397 N/A physical interaction ComPPI
PRIM1 KLHL20 25348397 N/A physical interaction ComPPI
PRIM1 LIPH 25348397 N/A physical interaction ComPPI
PRIM1 CCAR1 25348397 N/A physical interaction ComPPI
PRIM1 DUSP9 25348397 N/A physical interaction ComPPI
PRIM1 RNF31 25348397 N/A physical interaction ComPPI
PRIM1 DCAF10 25348397 N/A physical interaction ComPPI
PRIM1 NCAPH2 25348397 N/A physical interaction ComPPI
PRIM1 C6ORF141 25348397 N/A physical interaction ComPPI
PRIM1 AK9 25348397 N/A physical interaction ComPPI
PRIM1 CDK8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
H3C1 PRIM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PRIM1 TP53 11917009 14525934 N/A experimental interaction detection HPRD
TANK PRIM1 24234451 30561431 association virotrap IntAct

Visualization










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