Gene Information gene info

GENE:STX3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol STX3
FullNmae syntaxin 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11438
EnsembleID ENSG00000166900
Uniprot Q13277

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
STX3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
STX3 GO:0000149,GO:0001750,GO:0001917,GO:0005484,GO:0005515,GO:0005634,GO:0005773,GO:0005886,GO:0005886,GO:0005886,GO:0005911,GO:0006886,GO:0008021,GO:0008284,GO:0010468,GO:0012505,GO:0016324,GO:0030027,GO:0030425,GO:0030426,GO:0031175,GO:0031201,GO:0031201,GO:0031629,GO:0042470,GO:0042581,GO:0042582,GO:0042589,GO:0043005,GO:0045785,GO:0048278,GO:0048787,GO:0050544,GO:0050921,GO:0060291,GO:0070062,GO:0090174,GO:0098685,GO:0098794,GO:0098967,GO:0098978,GO:1903078,GO:2000010

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
STX3 hsa:6809 path:hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human)
STX3 hsa:6809 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 STX3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 STX3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 STX3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 STX3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 STX3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 STX3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 STX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 STX3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 STX3 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000031E12 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000A07C1 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000000B1C9 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000029979D STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000237CBD STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001925C1 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003D8730 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000029D793 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000019907A STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000137EDE STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000136174 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002D2333 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001B12A4 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000237AF9 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000148B91 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A760 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB35 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032EF64 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000284586 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003883FE STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000037D7E5 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000122ED0 STX3 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TXLNA STX3 25348397 N/A physical interaction ComPPI
CDC42 STX3 25348397 N/A physical interaction ComPPI
ZFYVE9 STX3 17693260 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,pull down,confocal microscopy ComPPI,IntAct
SNAP29 STX3 14525934 24234451 25348397 9852078 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
VAMP2 STX3 25348397 N/A physical interaction ComPPI
LMNA STX3 25348397 N/A physical interaction ComPPI
SYTL4 STX3 25348397 N/A physical interaction ComPPI
TRPC3 STX3 14525934 15623527 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RAB3B STX3 25348397 N/A physical interaction ComPPI
MSH6 STX3 25348397 N/A physical interaction ComPPI
HNRNPL STX3 25348397 N/A physical interaction ComPPI
SNAP25 STX3 14525934 25348397 7768895 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SNAP23 STX3 12828989 14525934 24234451 25348397 26359495 9701566 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
STXBP1 STX3 14525934 17363971 25348397 9045631 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYT1 STX3 25348397 N/A physical interaction ComPPI
STX4 STX3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STX1A STX3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STXBP2 STX3 10469351 10788461 12198139 14525934 18505797 25348397 26186194 26553929 27898060 7598732 7768895 9701566 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
SYT4 STX3 10397765 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
VAMP8 STX3 10336434 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
VAMP7 STX3 14525934 25348397 9614185 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
STX8 STX3 25348397 N/A physical interaction ComPPI
STXBP6 STX3 25348397 N/A physical interaction ComPPI
STXBP5 STX3 25348397 N/A physical interaction ComPPI
SYT7 STX3 14525934 25348397 7791877 N/A experimental interaction detection,in vitro ComPPI,HPRD
VAMP3 STX3 14525934 25348397 9614185 9701566 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RAB11A STX3 25348397 N/A physical interaction ComPPI
EVI5 STX3 25348397 N/A physical interaction ComPPI
STX3 CPLX2 14525934 25348397 27898060 8824312 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
STX3 STX6 25348397 N/A physical interaction ComPPI
STX3 GOSR1 25348397 N/A physical interaction ComPPI
STX3 STX5 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX3 YKT6 25348397 N/A physical interaction ComPPI
STX3 TBK1 25348397 N/A physical interaction ComPPI
STX3 VAMP4 25348397 N/A physical interaction ComPPI
STX3 TNFRSF10B 25348397 N/A physical interaction ComPPI
STX3 FGD1 25348397 N/A physical interaction ComPPI
STX3 LLGL1 25348397 N/A physical interaction ComPPI
STX3 PPIA 25348397 N/A physical interaction ComPPI
STX3 G3BP1 25348397 N/A physical interaction ComPPI
STX3 MAP3K2 25348397 N/A physical interaction ComPPI
STX3 ZWINT 25348397 N/A physical interaction ComPPI
STX3 NCBP2 25348397 N/A physical interaction ComPPI
STX3 SIN3B 25348397 N/A physical interaction ComPPI
STX3 SAMHD1 25348397 N/A physical interaction ComPPI
STX3 MYEF2 25348397 N/A physical interaction ComPPI
STX3 GAR1 25348397 N/A physical interaction ComPPI
STX3 TMEM132A 25348397 N/A physical interaction ComPPI
STX3 THOC2 25348397 N/A physical interaction ComPPI
STX3 FBXO31 25348397 N/A physical interaction ComPPI
STX3 YIPF5 25348397 N/A physical interaction ComPPI
STX3 MYO5B 25348397 N/A physical interaction ComPPI
STX3 TRIM25 25348397 N/A physical interaction ComPPI
STX3 EBAG9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX3 CREB3L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX3 RMDN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX3 CD79A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLMAP STX3 25348397 N/A physical interaction ComPPI
MANBAL STX3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX3 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
SYT1 STX3 1321498 27898060 7559535 stimulant N/A OmniPath
DAPK1 STX3 12730201 27898060 inhibition N/A OmniPath
CAMK2A STX3 11978810 27898060 inhibition N/A OmniPath
CSNK1G1 STX3 11846792 27898060 stimulant N/A OmniPath
STXBP6 STX3 12145319 27898060 inhibition N/A OmniPath
STX3 KCNA1 12114518 27898060 stimulant N/A OmniPath
UNC13B STX3 27898060 8999968 stimulant N/A OmniPath

Visualization