GENE:STX3
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | STX3 |
FullNmae | syntaxin 3 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:11438 |
EnsembleID | ENSG00000166900 |
Uniprot | Q13277 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
STX3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
STX3 | GO:0000149,GO:0001750,GO:0001917,GO:0005484,GO:0005515,GO:0005634,GO:0005773,GO:0005886,GO:0005886,GO:0005886,GO:0005911,GO:0006886,GO:0008021,GO:0008284,GO:0010468,GO:0012505,GO:0016324,GO:0030027,GO:0030425,GO:0030426,GO:0031175,GO:0031201,GO:0031201,GO:0031629,GO:0042470,GO:0042581,GO:0042582,GO:0042589,GO:0043005,GO:0045785,GO:0048278,GO:0048787,GO:0050544,GO:0050921,GO:0060291,GO:0070062,GO:0090174,GO:0098685,GO:0098794,GO:0098967,GO:0098978,GO:1903078,GO:2000010 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
STX3 | hsa:6809 | path:hsa04130 | SNARE interactions in vesicular transport - Homo sapiens (human) |
STX3 | hsa:6809 | path:hsa04721 | Synaptic vesicle cycle - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | STX3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA1 | STX3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | STX3 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA3 | STX3 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXA1 | STX3 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | STX3 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | STX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | STX3 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00000ED600 | STX3 | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS0000324096 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000031E12 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00000A07C1 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000000B1C9 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000029979D | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000237CBD | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00001925C1 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00003D8730 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000029D793 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00002152A8 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000019907A | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000137EDE | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000136174 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00002D2333 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00001B12A4 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000237AF9 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000148B91 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000075A760 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000075AB35 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000032EF64 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000021202F | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000284586 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00003883FE | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000037D7E5 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00002A8BC6 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000122ED0 | STX3 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TXLNA | STX3 | 25348397 | N/A | physical interaction | ComPPI |
CDC42 | STX3 | 25348397 | N/A | physical interaction | ComPPI |
ZFYVE9 | STX3 | 17693260 24234451 25348397 | colocalization,physical association | anti tag coimmunoprecipitation,pull down,confocal microscopy | ComPPI,IntAct |
SNAP29 | STX3 | 14525934 24234451 25348397 9852078 | physical association | two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid | ComPPI,HPRD,IntAct |
VAMP2 | STX3 | 25348397 | N/A | physical interaction | ComPPI |
LMNA | STX3 | 25348397 | N/A | physical interaction | ComPPI |
SYTL4 | STX3 | 25348397 | N/A | physical interaction | ComPPI |
TRPC3 | STX3 | 14525934 15623527 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
RAB3B | STX3 | 25348397 | N/A | physical interaction | ComPPI |
MSH6 | STX3 | 25348397 | N/A | physical interaction | ComPPI |
HNRNPL | STX3 | 25348397 | N/A | physical interaction | ComPPI |
SNAP25 | STX3 | 14525934 25348397 7768895 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SNAP23 | STX3 | 12828989 14525934 24234451 25348397 26359495 9701566 | physical association | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
STXBP1 | STX3 | 14525934 17363971 25348397 9045631 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
SYT1 | STX3 | 25348397 | N/A | physical interaction | ComPPI |
STX4 | STX3 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
STX1A | STX3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
STXBP2 | STX3 | 10469351 10788461 12198139 14525934 18505797 25348397 26186194 26553929 27898060 7598732 7768895 9701566 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
SYT4 | STX3 | 10397765 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
VAMP8 | STX3 | 10336434 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
VAMP7 | STX3 | 14525934 25348397 9614185 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
STX8 | STX3 | 25348397 | N/A | physical interaction | ComPPI |
STXBP6 | STX3 | 25348397 | N/A | physical interaction | ComPPI |
STXBP5 | STX3 | 25348397 | N/A | physical interaction | ComPPI |
SYT7 | STX3 | 14525934 25348397 7791877 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
VAMP3 | STX3 | 14525934 25348397 9614185 9701566 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
RAB11A | STX3 | 25348397 | N/A | physical interaction | ComPPI |
EVI5 | STX3 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | CPLX2 | 14525934 25348397 27898060 8824312 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
STX3 | STX6 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | GOSR1 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | STX5 | 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
STX3 | YKT6 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | TBK1 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | VAMP4 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | TNFRSF10B | 25348397 | N/A | physical interaction | ComPPI |
STX3 | FGD1 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | LLGL1 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | PPIA | 25348397 | N/A | physical interaction | ComPPI |
STX3 | G3BP1 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | MAP3K2 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | ZWINT | 25348397 | N/A | physical interaction | ComPPI |
STX3 | NCBP2 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | SIN3B | 25348397 | N/A | physical interaction | ComPPI |
STX3 | SAMHD1 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | MYEF2 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | GAR1 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | TMEM132A | 25348397 | N/A | physical interaction | ComPPI |
STX3 | THOC2 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | FBXO31 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | YIPF5 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | MYO5B | 25348397 | N/A | physical interaction | ComPPI |
STX3 | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
STX3 | EBAG9 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
STX3 | CREB3L1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
STX3 | RMDN3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
STX3 | CD79A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
SLMAP | STX3 | 25348397 | N/A | physical interaction | ComPPI |
MANBAL | STX3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
STX3 | DNAJC5 | 24234451 29997244 | physical association | bioluminescence resonance energy transfer | IntAct |
SYT1 | STX3 | 1321498 27898060 7559535 | stimulant | N/A | OmniPath |
DAPK1 | STX3 | 12730201 27898060 | inhibition | N/A | OmniPath |
CAMK2A | STX3 | 11978810 27898060 | inhibition | N/A | OmniPath |
CSNK1G1 | STX3 | 11846792 27898060 | stimulant | N/A | OmniPath |
STXBP6 | STX3 | 12145319 27898060 | inhibition | N/A | OmniPath |
STX3 | KCNA1 | 12114518 27898060 | stimulant | N/A | OmniPath |
UNC13B | STX3 | 27898060 8999968 | stimulant | N/A | OmniPath |