Gene Information gene info

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GENE：VPS4B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VPS4B
FullNmae vacuolar protein sorting 4 homolog B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10895
EnsembleID ENSG00000119541
Uniprot O75351

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VPS4B mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
VPS4B lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
VPS4B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
VPS4B GO:0000922,GO:0001525,GO:0001778,GO:0005515,GO:0005524,GO:0005634,GO:0005643,GO:0005737,GO:0005768,GO:0005813,GO:0005829,GO:0005886,GO:0006813,GO:0006914,GO:0006997,GO:0006997,GO:0007033,GO:0007080,GO:0010008,GO:0010824,GO:0010971,GO:0015031,GO:0016197,GO:0016197,GO:0016236,GO:0016887,GO:0030301,GO:0030496,GO:0031468,GO:0031902,GO:0032510,GO:0033993,GO:0036258,GO:0039702,GO:0042802,GO:0042803,GO:0043162,GO:0044877,GO:0046761,GO:0051261,GO:0060070,GO:0060856,GO:0061738,GO:0061764,GO:0061952,GO:0061952,GO:0070062,GO:0071985,GO:0090148,GO:0090543,GO:0090611,GO:0097352,GO:1901673,GO:1903542,GO:1903543,GO:1903724,GO:1904903,GO:1904903,GO:1904949

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
VPS4B hsa:9525 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)
VPS4B hsa:9525 path:hsa04144 Endocytosis - Homo sapiens (human)
VPS4B hsa:9525 path:hsa04217 Necroptosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 VPS4B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 VPS4B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP53 VPS4B 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 VPS4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA VPS4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF VPS4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 VPS4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 VPS4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS VPS4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A VPS4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 VPS4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000006FDD4 VPS4B 14697198 rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 VPS4B 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002FC5B0 VPS4B 20371350 21572407 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000006FDD4 VPS4B 14697198 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000070B1D VPS4B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000033EBB8 VPS4B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 VPS4B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F VPS4B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 VPS4B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 VPS4B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 VPS4B 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
VPS4B CHMP2B 25361965 interaction type N/A PTMCode2
CHMP2B VPS4B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CHMP2A VPS4B 14525934 15173323 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
VPS4B VPS4A 11563910 12594041 14525934 25348397 27898060 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
VPS4B CHMP1B 14505570 14525934 17928862 24234451 25348397 N/A experimental interaction detection,surface plasmon resonance,physical interaction,in vitro,surface plasmon resonance array ComPPI,HPRD,IntAct
VPS4B BABAM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VPS4B ELAVL1 25348397 N/A physical interaction ComPPI
VPS4B CHMP1A 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,surface plasmon resonance array,two hybrid prey pooling approach ComPPI,IntAct
VPS4B PDCD6IP 25348397 N/A physical interaction ComPPI
VPS4B CUL3 25348397 N/A physical interaction ComPPI
VPS4B CHMP4A 25348397 N/A physical interaction ComPPI
VPS4B ZPR1 25348397 N/A physical interaction ComPPI
VPS4B ZNRD2 25348397 N/A physical interaction ComPPI
VPS4B UBXN1 25348397 N/A physical interaction ComPPI
VPS4B UBQLN1 25348397 N/A physical interaction ComPPI
VPS4B YAP1 25348397 N/A physical interaction ComPPI
VPS4B UBQLN4 25348397 N/A physical interaction ComPPI
VPS4B TTLL12 25348397 N/A physical interaction ComPPI
VPS4B VPS26A 25348397 N/A physical interaction ComPPI
VPS4B AHCYL1 25348397 N/A physical interaction ComPPI
VPS4B ZFYVE19 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VPS4B UBE4B 25348397 N/A physical interaction ComPPI
VPS4B RAB5B 25348397 N/A physical interaction ComPPI
VPS4B NUP214 25348397 N/A physical interaction ComPPI
VPS4B TTC9C 25348397 N/A physical interaction ComPPI
VPS4B TYMS 25348397 N/A physical interaction ComPPI
VPS4B IGBP1 25348397 N/A physical interaction ComPPI
VPS4B USP34 25348397 N/A physical interaction ComPPI
VPS4B USP8 25348397 N/A physical interaction ComPPI
VPS4B ZNF585B 25348397 N/A physical interaction ComPPI
VPS4B HTRA2 25348397 N/A physical interaction ComPPI
VPS4B CHMP5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VPS4B NXF1 25348397 N/A physical interaction ComPPI
VPS4B EGFR 25348397 N/A physical interaction ComPPI
VPS4B BIRC2 25348397 N/A physical interaction ComPPI
VPS4B ITPA 25348397 N/A physical interaction ComPPI
VPS4B VTA1 25348397 N/A physical interaction ComPPI
VPS4B RBM14 25348397 N/A physical interaction ComPPI
VPS4B PRKCA 25348397 N/A physical interaction ComPPI
VPS4B VPS13A 25348397 N/A physical interaction ComPPI
VPS4B VPS45 25348397 N/A physical interaction ComPPI
VPS4B IST1 25348397 N/A physical interaction ComPPI
VPS4B NSF 25348397 N/A physical interaction ComPPI
VPS4B PPP1R8 25348397 N/A physical interaction ComPPI
VPS4B EPHA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VPS4B RALA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VPS4B EFR3A 25348397 N/A physical interaction ComPPI
VPS4B CHMP2B 25348397 N/A nuclear magnetic resonance,physical interaction,surface plasmon resonance array ComPPI
VPS4B KATNAL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUMA1 VPS4B 24234451 30021884 physical association cross-linking study IntAct
H1-5 VPS4B 24234451 30021884 physical association cross-linking study IntAct

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