Gene Information gene info

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GENE：RIOK3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RIOK3
FullNmae RIO kinase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11451
EnsembleID ENSG00000101782
Uniprot O14730

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RIOK3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RIOK3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RIOK3 GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005829,GO:0005829,GO:0007059,GO:0016310,GO:0030490,GO:0030490,GO:0030688,GO:0030688,GO:0031333,GO:0032728,GO:0039534,GO:0043124,GO:0045087,GO:0045089,GO:0046872,GO:0051607,GO:0071359,GO:0089720,GO:0098586,GO:0106310,GO:1990786

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RIOK3 UBC 19285159 23180781 physical association protein array,pull down InnateDB
RIOK3 IRF3 23180781 24807708 physical association anti tag coimmunoprecipitation InnateDB
RIOK3 TBK1 23180781 24807708 physical association anti tag coimmunoprecipitation InnateDB
CASP10 RIOK3 21988832 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 RIOK3 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RIOK3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A RIOK3 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 RIOK3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RIOK3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RIOK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RIOK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RIOK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RIOK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RIOK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RIOK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RIOK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 RIOK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000016D2D4 RIOK3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 RIOK3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000821E0 RIOK3 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS0000076995 RIOK3 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS0000272A3D RIOK3 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS0000166778 RIOK3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 RIOK3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000008B558 RIOK3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 RIOK3 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RIOK3 IFIH1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
BCL2L11 RIOK3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDC42 RIOK3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PAK2 RIOK3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAGEA6 RIOK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CALM1 RIOK3 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
RACK1 RIOK3 25348397 N/A physical interaction ComPPI
UBC RIOK3 25348397 N/A physical interaction ComPPI
UBE2N RIOK3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
IRF3 RIOK3 24234451 24807708 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
XPO1 RIOK3 25348397 N/A physical interaction ComPPI
PSMC4 RIOK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CASP10 RIOK3 19557502 21988832 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,confocal microscopy ComPPI,IntAct
SSR4 RIOK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA1 RIOK3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
SMURF1 RIOK3 25348397 N/A physical interaction ComPPI
TBK1 RIOK3 24234451 24807708 25348397 association,physical association anti tag coimmunoprecipitation ComPPI,IntAct
ELAVL1 RIOK3 25348397 N/A physical interaction ComPPI
PSMB1 RIOK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2V1 RIOK3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
ARL1 RIOK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
XRCC3 RIOK3 25348397 N/A physical interaction ComPPI
RUVBL2 RIOK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO1C RIOK3 25348397 N/A physical interaction ComPPI
FBL RIOK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CREB3L3 RIOK3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXO25 RIOK3 25348397 N/A physical interaction ComPPI
RIOK3 MOV10 25348397 N/A physical interaction ComPPI
RIOK3 SUPT6H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIOK3 TM9SF4 25348397 N/A physical interaction ComPPI
RIOK3 MMGT1 25348397 N/A physical interaction ComPPI
RIOK3 ZMAT3 25348397 N/A physical interaction ComPPI
RIOK3 OSBPL5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIOK3 TULP3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
RIOK3 IFIH1 24234451 25348397 25865883 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,confocal microscopy ComPPI,IntAct
CALM2 RIOK3 17353931 24234451 physical association anti bait coimmunoprecipitation IntAct
RIOK3 IRF3 24807708 27898060 N/A N/A OmniPath
CASP10 RIOK3 21988832 27898060 N/A N/A OmniPath
RIOK3 IFIH1 25865883 27898060 N/A N/A OmniPath
RIOK3 TBK1 24807708 27898060 N/A N/A OmniPath

Visualization










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