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GENE：EFHD2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EFHD2
FullNmae EF-hand domain family member D2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28670
EnsembleID ENSG00000142634
Uniprot Q96C19

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EFHD2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EFHD2 GO:0005509,GO:0045121,GO:0045296

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CASP9 EFHD2 19118655 23180781 physical association anti tag coimmunoprecipitation InnateDB
EFHD2 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR EFHD2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 EFHD2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 EFHD2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 EFHD2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 EFHD2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 EFHD2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 EFHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000007FBA EFHD2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000EED18 EFHD2 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00001B341F EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002D2333 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A EFHD2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000016FF9C EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C85C7 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041E11D EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000032BDF4 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A9CF EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D4AB5 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000024A59E EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000077DDE EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C403E EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 EFHD2 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BE495 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000913AC EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000204177 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 EFHD2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 EFHD2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC EFHD2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F7766 EFHD2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000029EBD EFHD2 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 EFHD2 22135298 phosphorylation N/A PhosphoSite
CDK2 EFHD2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
ARPC3 EFHD2 25348397 N/A physical interaction ComPPI
GLRX3 EFHD2 25348397 N/A physical interaction ComPPI
KEAP1 EFHD2 25348397 N/A physical interaction ComPPI
PTPN11 EFHD2 25348397 N/A physical interaction ComPPI
CDH1 EFHD2 25348397 N/A physical interaction ComPPI
MYO18A EFHD2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2E2 EFHD2 25348397 N/A physical interaction ComPPI
USP11 EFHD2 25348397 N/A physical interaction ComPPI
RAD51D EFHD2 16710300 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
ELAVL1 EFHD2 25348397 N/A physical interaction ComPPI
RAE1 EFHD2 25348397 N/A physical interaction ComPPI
RCN1 EFHD2 25348397 N/A physical interaction ComPPI
ACTR2 EFHD2 25348397 N/A physical interaction ComPPI
PAN2 EFHD2 25348397 N/A physical interaction ComPPI
CHMP4A EFHD2 25348397 N/A physical interaction ComPPI
MYH9 EFHD2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC2 EFHD2 25348397 N/A physical interaction ComPPI
ARPC4 EFHD2 25348397 N/A physical interaction ComPPI
TMOD1 EFHD2 25348397 N/A physical interaction ComPPI
ENO2 EFHD2 25348397 N/A physical interaction ComPPI
COASY EFHD2 25348397 N/A physical interaction ComPPI
LIMA1 EFHD2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FSD1 EFHD2 25348397 N/A physical interaction ComPPI
IDH1 EFHD2 25348397 N/A physical interaction ComPPI
GMPS EFHD2 25348397 N/A physical interaction ComPPI
DCK EFHD2 25348397 N/A physical interaction ComPPI
FBXO6 EFHD2 25348397 N/A physical interaction ComPPI
VARS1 EFHD2 25348397 N/A physical interaction ComPPI
APP EFHD2 25348397 N/A physical interaction ComPPI
LRRK2 EFHD2 25348397 N/A physical interaction ComPPI
GFUS EFHD2 25348397 N/A physical interaction ComPPI
MYH10 EFHD2 24234451 30021884 physical association cross-linking study IntAct
CDK1 EFHD2 24917152 27898060 N/A N/A OmniPath

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