GENE：CLCF1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CLCF1 |
| FullNmae | cardiotrophin like cytokine factor 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17412 |
| EnsembleID | ENSG00000175505 |
| Uniprot | Q9UBD9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CLCF1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CLCF1 | GO:0002639,GO:0005102,GO:0005125,GO:0005125,GO:0005127,GO:0005515,GO:0005576,GO:0005576,GO:0005576,GO:0005576,GO:0005615,GO:0007166,GO:0007259,GO:0007259,GO:0008083,GO:0008284,GO:0019221,GO:0030183,GO:0030890,GO:0030890,GO:0042531,GO:0042531,GO:0042531,GO:0043524,GO:0048295,GO:0048711,GO:0097058,GO:0097058,GO:0097059,GO:0097059 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CLCF1 | hsa:23529 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
| CLCF1 | hsa:23529 | path:hsa04630 | JAK-STAT signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | CLCF1 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | CLCF1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CLCF1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CLCF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CLCF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CLCF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CLCF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | CLCF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CLCF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CLCF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | CLCF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR2 | CLCF1 | 21182203 24234451 25348397 | association | affinity chromatography technology | ComPPI,IntAct |
| PARK7 | CLCF1 | 25348397 | N/A | physical interaction | ComPPI |
| CLCF1 | CRLF1 | 10966616 14525934 16782820 24234451 25348397 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| CLCF1 | CNTFR | 10966616 11285233 11294841 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CLCF1 | IL6ST | 27898060 9143707 | stimulant | N/A | OmniPath |
| CLCF1 | CNTFR | 10966616 11285233 11294841 27898060 | stimulant | N/A | OmniPath |
| CLCF1 | CRLF1 | 10966616 27898060 | stimulant | N/A | OmniPath |