Gene Information gene info

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GENE：AK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AK1
FullNmae adenylate kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:361
EnsembleID ENSG00000106992
Uniprot P00568

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AK1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AK1 GO:0001520,GO:0004017,GO:0004017,GO:0004550,GO:0005524,GO:0005737,GO:0005829,GO:0005829,GO:0005829,GO:0006172,GO:0009142,GO:0015949,GO:0016310,GO:0046033,GO:0046034,GO:0046899,GO:0046940,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AK1 hsa:203 path:hsa00230 Purine metabolism - Homo sapiens (human)
AK1 hsa:203 path:hsa00730 Thiamine metabolism - Homo sapiens (human)
AK1 hsa:203 path:hsa01100 Metabolic pathways - Homo sapiens (human)
AK1 hsa:203 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)
AK1 hsa:203 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AKT1 AK1 12042314 23180781 phosphorylation reaction in-gel kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
SMARCA4 AK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 AK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR AK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004E008F AK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA AK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000086A4D AK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E AK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F31F4 AK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 AK1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CD2BP2 AK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FHL2 AK1 12432079 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GEMIN5 AK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM63 AK1 25348397 N/A physical interaction ComPPI
OGT AK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUCLG2 AK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRE11 AK1 25348397 N/A physical interaction ComPPI
TERF1 AK1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TINF2 AK1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
RAB11FIP2 AK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRD4 AK1 25348397 N/A physical interaction ComPPI
TERF2IP AK1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TIA1 AK1 25348397 N/A physical interaction ComPPI
IDH1 AK1 25348397 N/A physical interaction ComPPI
NBAS AK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AK1 KMT2C 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AK1 APP 25348397 N/A physical interaction ComPPI
AK1 NXF1 25348397 N/A physical interaction ComPPI
AK1 DECR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AK1 SLC12A2 25348397 N/A physical interaction ComPPI
AK1 COBLL1 25348397 N/A physical interaction ComPPI
AK1 PCF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AK1 KDM3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AK1 BUD13 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AK1 UTP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AK1 B3GLCT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPU AK1 24234451 30021884 physical association cross-linking study IntAct
AKT1 AK1 10653665 12042314 12107176 27898060 N/A N/A OmniPath

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