Gene Information gene info

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GENE：AP3B2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AP3B2
FullNmae adaptor related protein complex 3 subunit beta 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:567
EnsembleID ENSG00000103723
Uniprot Q13367

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AP3B2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AP3B2 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
AP3B2 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
AP3B2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AP3B2 GO:0005769,GO:0005794,GO:0006886,GO:0008089,GO:0016183,GO:0016192,GO:0030123,GO:0030665,GO:0035654,GO:0036465,GO:0046907,GO:0048490,GO:0048490,GO:0097708,GO:0098793,GO:1904115

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AP3B2 hsa:8120 path:hsa04142 Lysosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 AP3B2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 AP3B2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA AP3B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AP3B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AP3B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AP3B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AP3B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE AP3B2 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 AP3B2 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F AP3B2 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 AP3B2 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA AP3B2 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 AP3B2 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000913AC AP3B2 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A AP3B2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 AP3B2 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AP3B2 ATM 25361965 interaction type N/A PTMCode2
ATM AP3B2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
AP3M1 AP3B2 25348397 N/A physical interaction ComPPI
NTRK1 AP3B2 25348397 N/A physical interaction ComPPI
ADAP1 AP3B2 12565890 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RUFY1 AP3B2 25348397 N/A physical interaction ComPPI
ATM AP3B2 14525934 25348397 9707615 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
CLTC AP3B2 14525934 25348397 9545220 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARRB2 AP3B2 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AP3D1 AP3B2 25348397 N/A physical interaction ComPPI
EDA AP3B2 25348397 N/A physical interaction ComPPI
AP3B2 AP3S1 14525934 25348397 9118953 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
AP3B2 DTNBP1 25348397 N/A physical interaction ComPPI
AP3B2 CSNK1A1 10930456 14525934 N/A experimental interaction detection HPRD

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