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GENE：AP3M2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AP3M2
FullNmae adaptor related protein complex 3 subunit mu 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:570
EnsembleID ENSG00000070718
Uniprot P53677

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AP3M2 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
AP3M2 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
AP3M2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AP3M2 GO:0005769,GO:0005794,GO:0006886,GO:0006897,GO:0008089,GO:0016183,GO:0030119,GO:0030123,GO:0030131,GO:0030659,GO:0031410,GO:0035654,GO:0036465,GO:0046907,GO:0048490,GO:0098793,GO:1904115

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AP3M2 hsa:10947 path:hsa04142 Lysosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 AP3M2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 AP3M2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 AP3M2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 AP3M2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC AP3M2 19296470 rna interference,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00003380CC AP3M2 19296470 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000F31F4 AP3M2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 AP3M2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 AP3M2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000AA464 AP3M2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003808EC AP3M2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000192A75 AP3M2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000065FDF AP3M2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000079D48 AP3M2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A6D0C AP3M2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000029D9F1 AP3M2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003E5E03 AP3M2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000277201 AP3M2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 AP3M2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 AP3M2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 AP3M2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GRK5 AP3M2 25348397 N/A physical interaction ComPPI
XPO1 AP3M2 25348397 N/A physical interaction ComPPI
AP3D1 AP3M2 25348397 N/A physical interaction ComPPI
EDA AP3M2 25348397 N/A physical interaction ComPPI
AP3B1 AP3M2 25348397 N/A physical interaction ComPPI
AP3S1 AP3M2 25348397 N/A physical interaction ComPPI
AP3S2 AP3M2 25348397 N/A physical interaction ComPPI

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