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GENE：AP3S2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AP3S2
FullNmae adaptor related protein complex 3 subunit sigma 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:571
EnsembleID ENSG00000157823
Uniprot P59780

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AP3S2 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
AP3S2 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
AP3S2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AP3S2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AP3S2 GO:0005769,GO:0005794,GO:0006886,GO:0006896,GO:0008089,GO:0016183,GO:0016192,GO:0016192,GO:0030123,GO:0030123,GO:0030659,GO:0035654,GO:0036465,GO:0043231,GO:0043231,GO:0046907,GO:0048490,GO:0060155,GO:0098793,GO:1903232,GO:1904115

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AP3S2 hsa:10239 path:hsa04142 Lysosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR AP3S2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 AP3S2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA AP3S2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AP3S2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 AP3S2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AP3S2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AP3S2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AP3S2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000035CC3E AP3S2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000042E1F AP3S2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075D814 AP3S2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 AP3S2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004E008F AP3S2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC AP3S2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 AP3S2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 AP3S2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F AP3S2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 AP3S2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D AP3S2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000A057E AP3S2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 AP3S2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000821E0 AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000C85B2 AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000B989F AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000039A052 AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000045147B AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001A7F58 AP3S2 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AP3B1 AP3S2 25361965 interaction type N/A PTMCode2
AP3S2 AP3B1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
AP3M1 AP3S2 25348397 N/A physical interaction ComPPI
XPO1 AP3S2 25348397 N/A physical interaction ComPPI
E2F4 AP3S2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HUWE1 AP3S2 25348397 N/A physical interaction ComPPI
ARF6 AP3S2 25348397 N/A physical interaction ComPPI
AP3D1 AP3S2 14525934 15469849 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
AP3B1 AP3S2 14525934 25348397 27898060 9182526 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
TRIM25 AP3S2 25348397 N/A physical interaction ComPPI
DTNBP1 AP3S2 25348397 N/A physical interaction ComPPI
AP3S1 AP3S2 14525934 25348397 9118953 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
AP3S2 ARF1 25348397 N/A physical interaction ComPPI
AP3S2 RNF13 25348397 N/A physical interaction ComPPI
AP3S2 TMEM63A 25348397 N/A physical interaction ComPPI
AP3S2 AP3M2 25348397 N/A physical interaction ComPPI

Visualization










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