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GENE：ATXN10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATXN10
FullNmae ataxin 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10549
EnsembleID ENSG00000130638
Uniprot Q9UBB4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATXN10 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATXN10 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATXN10 GO:0005515,GO:0005615,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0007399,GO:0016020,GO:0030425,GO:0031175,GO:0031175,GO:0043025,GO:0048471,GO:0060271

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATXN10 hsa:25814 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ATXN10 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 ATXN10 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 ATXN10 19559773 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ATXN10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC ATXN10 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 ATXN10 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000065D58 ATXN10 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000183BED ATXN10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000009262D ATXN10 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PLK1 ATXN10 22135298 phosphorylation N/A PhosphoSite
AURKB ATXN10 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SAP18 ATXN10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPA8 ATXN10 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GOLGA1 ATXN10 25348397 N/A physical interaction ComPPI
MAGEA6 ATXN10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VCP ATXN10 25348397 N/A physical interaction ComPPI
PPP1R12A ATXN10 25348397 N/A physical interaction ComPPI
CUL3 ATXN10 25348397 N/A physical interaction ComPPI
SERPINH1 ATXN10 25348397 N/A physical interaction ComPPI
DLD ATXN10 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ILK ATXN10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPA1A ATXN10 25348397 N/A physical interaction ComPPI
HSPA1B ATXN10 25348397 N/A physical interaction ComPPI
MYC ATXN10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CFTR ATXN10 25348397 N/A physical interaction ComPPI
ABCE1 ATXN10 25348397 N/A physical interaction ComPPI
EGFR ATXN10 15657067 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PHB2 ATXN10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPB1 ATXN10 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
CENPJ ATXN10 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
UBE2A ATXN10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CA9 ATXN10 25348397 N/A physical interaction ComPPI
MAGED1 ATXN10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
LIMS1 ATXN10 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ABCA1 ATXN10 25348397 N/A physical interaction ComPPI
PTPRN ATXN10 25348397 N/A physical interaction ComPPI
DUSP22 ATXN10 25348397 N/A physical interaction ComPPI
LAMB3 ATXN10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HTR6 ATXN10 24234451 25348397 28298427 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
GNB2 ATXN10 14525934 16498633 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
TNFRSF14 ATXN10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CEP162 ATXN10 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CEP152 ATXN10 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GNB1 ATXN10 25348397 N/A physical interaction ComPPI
STYXL1 ATXN10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
STOM ATXN10 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
ATXN10 BSG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ATXN10 GSTK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ATXN10 FN1 25348397 N/A physical interaction ComPPI
ATXN10 MRPS16 25348397 N/A physical interaction ComPPI
ATXN10 GLS 25348397 N/A physical interaction ComPPI
ATXN10 CCDC8 25348397 N/A physical interaction ComPPI
ATXN10 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATXN10 SCLT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATXN10 TUBA1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATXN10 MTMR14 25348397 N/A physical interaction ComPPI
ATXN10 PTP4A3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ATXN10 PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ATXN10 RAB5IF 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ATXN10 WRAP73 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSCB ATXN10 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
MKI67 ATXN10 24234451 26949251 association anti tag coimmunoprecipitation IntAct
PTGER4 ATXN10 24234451 28298427 physical association ubiquitin reconstruction IntAct
OGT ATXN10 16714295 27898060 N/A N/A OmniPath
PLK1 ATXN10 21857149 27898060 inhibition N/A OmniPath
AURKB ATXN10 25666058 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00007C6B78 ATXN10 27087310 direct interaction,inhibition N/A NPInter

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