GENE:BIN3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | BIN3 |
| FullNmae | bridging integrator 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1054 |
| EnsembleID | ENSG00000147439 |
| Uniprot | Q9NQY0 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| BIN3 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BIN3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| BIN3 | GO:0000917,GO:0005515,GO:0005737,GO:0006897,GO:0007015,GO:0008093,GO:0008104,GO:0008289,GO:0009826,GO:0010591,GO:0014839,GO:0015629,GO:0048741,GO:0051666,GO:0061640,GO:0097320 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | BIN3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | BIN3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | BIN3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | BIN3 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | BIN3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | BIN3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | BIN3 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000A07C1 | BIN3 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00001C770D | BIN3 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000032015F | BIN3 | 25416803 27666871 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TXLNA | BIN3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| DDIT4L | BIN3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PICK1 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| SNX1 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| SYNCRIP | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| PYGB | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| GTF3C3 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| PEX11B | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| SNX5 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| SEC63 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| DNMBP | BIN3 | 18654987 24234451 25348397 | physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction | ComPPI,IntAct |
| SORT1 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| UBL5 | BIN3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ERH | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| SHMT2 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| COG1 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| COG7 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| RPRD1B | BIN3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| GINS4 | BIN3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| C14ORF119 | BIN3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| FBXO8 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| AZU1 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| PCM1 | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
| POLR1C | BIN3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| NXF1 | BIN3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| BIN3 | OSBPL1A | 25348397 | N/A | physical interaction | ComPPI |
| BIN3 | ARHGEF37 | 25348397 | N/A | physical interaction | ComPPI |
| BIN3 | GTF3C6 | 25348397 | N/A | physical interaction | ComPPI |
| CI | BIN3 | 25348397 | N/A | physical interaction | ComPPI |
