GENE:BRWD1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | BRWD1 |
| FullNmae | bromodomain and WD repeat domain containing 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:12760 |
| EnsembleID | ENSG00000185658 |
| Uniprot | Q9NSI6 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| BRWD1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| BRWD1 | GO:0003674,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005730,GO:0005829,GO:0006357,GO:0007010,GO:0007010,GO:0008360,GO:0008360 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | BRWD1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | BRWD1 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | BRWD1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | BRWD1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | BRWD1 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | BRWD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002C0FCB | BRWD1 | 20371350 21572407 23313552 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS00000CBE63 | BRWD1 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00000600E6 | BRWD1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000B59A2 | BRWD1 | 23313552 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS0000171CD1 | BRWD1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00004AC389 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FF9C | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC379 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001D4A78 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | BRWD1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | BRWD1 | 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC864 | BRWD1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000183BED | BRWD1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | BRWD1 | 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002DD349 | BRWD1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | BRWD1 | 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | BRWD1 | 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | BRWD1 | 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000028BB8 | BRWD1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001AFC71 | BRWD1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000024DFCE | BRWD1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F31F4 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000079F78 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001597DC | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F859B | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000453664 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000E7139 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000210075 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BCD9C | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045E0EC | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EB9FC | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000345DEB | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000153377 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170CF4 | BRWD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFBE3 | BRWD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000050CCE0 | BRWD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | BRWD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001EB3 | BRWD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A9CF | BRWD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | BRWD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AAA0 | BRWD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CALM1 | BRWD1 | 25348397 | N/A | physical interaction | ComPPI |
| APPL1 | BRWD1 | 25348397 | N/A | physical interaction | ComPPI |
| COPS5 | BRWD1 | 25348397 | N/A | physical interaction | ComPPI |
| CUL3 | BRWD1 | 25348397 | N/A | physical interaction | ComPPI |
| SMARCA4 | BRWD1 | 12889071 25348397 27898060 | N/A | physical interaction,in vitro,in vivo | ComPPI,OmniPath |
| MYC | BRWD1 | 21150319 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| RDX | BRWD1 | 25348397 | N/A | physical interaction | ComPPI |
| CUL4A | BRWD1 | 25348397 | N/A | physical interaction | ComPPI |
| DDB1 | BRWD1 | 25348397 | N/A | physical interaction | ComPPI |
| STAT3 | BRWD1 | 25348397 | N/A | physical interaction | ComPPI |
| BRWD1 | UBXN7 | 18775313 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BRWD1 | APP | 25348397 | N/A | physical interaction | ComPPI |
| BRWD1 | MYO5C | 25348397 | N/A | physical interaction | ComPPI |
| BRWD1 | MMGT1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BRWD1 | CBX6 | 21282530 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| ITGB1 | BRWD1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| PDIA3 | BRWD1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
