GENE:CDK17
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CDK17 |
| FullNmae | cyclin dependent kinase 17 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:8750 |
| EnsembleID | ENSG00000059758 |
| Uniprot | Q00537 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CDK17 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CDK17 | GO:0000083,GO:0004672,GO:0004693,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0006468,GO:0006468,GO:0051726,GO:0106310 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | CDK17 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | CDK17 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CDK17 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | CDK17 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CDK17 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | CDK17 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000122ED0 | CDK17 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000AA464 | CDK17 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001EFEC1 | CDK17 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | CDK17 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000010BD8D | CDK17 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F4657 | CDK17 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F7766 | CDK17 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000029EBD | CDK17 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | CDK17 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | CDK17 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | CDK17 | 21572407 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | CDK17 | 21572407 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | CDK17 | 21572407 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | CDK17 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BICDL2 | CDK17 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| DPY30 | CDK17 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| BAG3 | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAG | CDK17 | 14525934 15324660 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
| NOP10 | CDK17 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| YWHAB | CDK17 | 24234451 24255178 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GAPDH | CDK17 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| YWHAZ | CDK17 | 14525934 15161933 24234451 25348397 | physical association | experimental interaction detection,pull down,in vitro | ComPPI,HPRD,IntAct |
| UBC | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| EPHA2 | CDK17 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| PPP2CB | CDK17 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| PPP2R5E | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAQ | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| UNC45A | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| MMS19 | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2R2A | CDK17 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| TUBGCP3 | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| CDK16 | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| DHPS | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| CDKN2B | CDK17 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM25 | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2R3A | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| DCAF7 | CDK17 | 24234451 25348397 27173435 | association,physical association | physical interaction,tandem affinity purification,inference by socio-affinity scoring | ComPPI,IntAct |
| PFDN2 | CDK17 | 25348397 | N/A | physical interaction | ComPPI |
| CDK17 | TDRD7 | 10727952 14525934 14603251 24234451 25348397 | association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| CDK17 | APP | 25348397 | N/A | physical interaction | ComPPI |
| CDK17 | PRKACG | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| CDK17 | PTMA | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| CDK17 | CDK14 | 25348397 | N/A | physical interaction | ComPPI |
| CDK17 | CDK1 | 25348397 | N/A | physical interaction | ComPPI |
| CDK17 | SUGP1 | 25348397 | N/A | physical interaction | ComPPI |
| CDK17 | CUSTOS | 25348397 | N/A | physical interaction | ComPPI |
| CDK17 | FEM1A | 25348397 | N/A | physical interaction | ComPPI |
| CDK17 | MANSC1 | 25348397 | N/A | physical interaction | ComPPI |
| CDK17 | HDGFL3 | 25348397 | N/A | physical interaction | ComPPI |
| CDK17 | PTBP3 | 22575643 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| CDK17 | TGFBR1 | 14525934 15761153 | N/A | experimental interaction detection | HPRD |
| CDK17 | CDK17 | 14525934 17192257 | N/A | experimental interaction detection | HPRD |
