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GENE：DCUN1D2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DCUN1D2
FullNmae defective in cullin neddylation 1 domain containing 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20328
EnsembleID ENSG00000150401
Uniprot Q6PH85

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DCUN1D2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DCUN1D2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DCUN1D2 GO:0000151,GO:0005515,GO:0005634,GO:0005737,GO:0031624,GO:0032182,GO:0045116,GO:0097602,GO:0097602,GO:2000434,GO:2000436

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DCUN1D2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 DCUN1D2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
HIF1A DCUN1D2 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
MYC DCUN1D2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DCUN1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DCUN1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DCUN1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DCUN1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 DCUN1D2 20584899 rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 DCUN1D2 20584899 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection TarBase
URS000003ABC4 DCUN1D2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002B2B5C DCUN1D2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000508C13 DCUN1D2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D DCUN1D2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 DCUN1D2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 DCUN1D2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 DCUN1D2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 DCUN1D2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 DCUN1D2 19617556 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCUN1D1 DCUN1D2 25348397 N/A physical interaction ComPPI
RNF7 DCUN1D2 25348397 N/A physical interaction ComPPI
RBX1 DCUN1D2 25348397 N/A physical interaction ComPPI
CUL3 DCUN1D2 19617556 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2N DCUN1D2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
CUL2 DCUN1D2 19617556 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL4B DCUN1D2 19617556 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL1 DCUN1D2 19617556 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL4A DCUN1D2 19617556 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELOB DCUN1D2 25348397 N/A physical interaction ComPPI
CAND1 DCUN1D2 25348397 N/A physical interaction ComPPI
UBA1 DCUN1D2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2V1 DCUN1D2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2M DCUN1D2 19617556 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAP3K1 DCUN1D2 25348397 N/A physical interaction ComPPI
APP DCUN1D2 25348397 N/A physical interaction ComPPI
UBE2F DCUN1D2 25348397 N/A physical interaction ComPPI

Visualization










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