GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
FAM189A2 |
FullNmae |
endosomal transmembrane epsin interactor 1 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:24820 |
EnsembleID |
ENSG00000135063 |
Uniprot |
Q15884 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
FAM189A2 |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
FAM189A2 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
ESR1 |
FAM189A2 |
21878914
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
ETS1 |
FAM189A2 |
20019798
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
GATA3 |
FAM189A2 |
21878914
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
FOXA1 |
FAM189A2 |
18971253
21878914
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
CTCF |
FAM189A2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
FAM189A2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
GATA2 |
FAM189A2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
FAM189A2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00000F31F4 |
FAM189A2 |
19074876
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS00000B59A2 |
FAM189A2 |
19074876
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
BAG3 |
FAM189A2 |
14525934
16189514
25348397
|
N/A |
two hybrid,physical interaction,two hybrid |
ComPPI,HPRD |
YWHAG |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRIM32 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
OPTN |
FAM189A2 |
21516116
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
DNAJC1 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
WWP1 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
SLC9A1 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
YWHAB |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
YWHAZ |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
WWP2 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
STAM2 |
FAM189A2 |
21516116
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
YWHAQ |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
ANKRD13A |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
NEDD4L |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
STXBP4 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
SFN |
FAM189A2 |
14525934
16189514
25348397
|
N/A |
two hybrid,physical interaction,two hybrid |
ComPPI,HPRD |
YWHAE |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
ADGRL1 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
ITCH |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
TAX1BP1 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
WWOX |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
NEDD4 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
PIGA |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
FZD2 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBQLN1 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
HECW2 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
CALCOCO2 |
FAM189A2 |
21516116
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
GJA1 |
FAM189A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
UBXN1 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
FAM189B |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
SLC27A3 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
CUEDC1 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
CTDNEP1 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
PDE3B |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
TBL2 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
HMGCR |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
AGPAT3 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
SLC12A6 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
SLC12A4 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
CYP51A1 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
SLC12A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
TMEM259 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
EPHX1 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
ANO6 |
25348397
|
N/A |
physical interaction |
ComPPI |
FAM189A2 |
HERC3 |
25348397
|
N/A |
physical interaction |
ComPPI |
Visualization