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GENE：FAM189A2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FAM189A2
FullNmae endosomal transmembrane epsin interactor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24820
EnsembleID ENSG00000135063
Uniprot Q15884

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FAM189A2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR FAM189A2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 FAM189A2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 FAM189A2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 FAM189A2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 FAM189A2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF FAM189A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FAM189A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 FAM189A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FAM189A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 FAM189A2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 FAM189A2 19074876 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
BAG3 FAM189A2 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
YWHAG FAM189A2 25348397 N/A physical interaction ComPPI
TRIM32 FAM189A2 25348397 N/A physical interaction ComPPI
OPTN FAM189A2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DNAJC1 FAM189A2 25348397 N/A physical interaction ComPPI
WWP1 FAM189A2 25348397 N/A physical interaction ComPPI
SLC9A1 FAM189A2 25348397 N/A physical interaction ComPPI
YWHAB FAM189A2 25348397 N/A physical interaction ComPPI
YWHAZ FAM189A2 25348397 N/A physical interaction ComPPI
WWP2 FAM189A2 25348397 N/A physical interaction ComPPI
STAM2 FAM189A2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
YWHAQ FAM189A2 25348397 N/A physical interaction ComPPI
ANKRD13A FAM189A2 25348397 N/A physical interaction ComPPI
NEDD4L FAM189A2 25348397 N/A physical interaction ComPPI
STXBP4 FAM189A2 25348397 N/A physical interaction ComPPI
SFN FAM189A2 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
YWHAE FAM189A2 25348397 N/A physical interaction ComPPI
ADGRL1 FAM189A2 25348397 N/A physical interaction ComPPI
ITCH FAM189A2 25348397 N/A physical interaction ComPPI
TAX1BP1 FAM189A2 25348397 N/A physical interaction ComPPI
WWOX FAM189A2 25348397 N/A physical interaction ComPPI
NEDD4 FAM189A2 25348397 N/A physical interaction ComPPI
PIGA FAM189A2 25348397 N/A physical interaction ComPPI
FZD2 FAM189A2 25348397 N/A physical interaction ComPPI
UBQLN1 FAM189A2 25348397 N/A physical interaction ComPPI
HECW2 FAM189A2 25348397 N/A physical interaction ComPPI
CALCOCO2 FAM189A2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GJA1 FAM189A2 25348397 N/A physical interaction ComPPI
FAM189A2 UBXN1 25348397 N/A physical interaction ComPPI
FAM189A2 FAM189B 25348397 N/A physical interaction ComPPI
FAM189A2 SLC27A3 25348397 N/A physical interaction ComPPI
FAM189A2 CUEDC1 25348397 N/A physical interaction ComPPI
FAM189A2 CTDNEP1 25348397 N/A physical interaction ComPPI
FAM189A2 PDE3B 25348397 N/A physical interaction ComPPI
FAM189A2 TBL2 25348397 N/A physical interaction ComPPI
FAM189A2 HMGCR 25348397 N/A physical interaction ComPPI
FAM189A2 AGPAT3 25348397 N/A physical interaction ComPPI
FAM189A2 SLC12A6 25348397 N/A physical interaction ComPPI
FAM189A2 SLC12A4 25348397 N/A physical interaction ComPPI
FAM189A2 CYP51A1 25348397 N/A physical interaction ComPPI
FAM189A2 SLC12A2 25348397 N/A physical interaction ComPPI
FAM189A2 TMEM259 25348397 N/A physical interaction ComPPI
FAM189A2 EPHX1 25348397 N/A physical interaction ComPPI
FAM189A2 ANO6 25348397 N/A physical interaction ComPPI
FAM189A2 HERC3 25348397 N/A physical interaction ComPPI

Visualization










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