Gene Information gene info

GENE:FBXL12

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FBXL12
FullNmae F-box and leucine rich repeat protein 12
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13611
EnsembleID ENSG00000127452
Uniprot Q9NXK8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FBXL12 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FBXL12 GO:0005515,GO:0005829,GO:0016567,GO:0019005,GO:0031146

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 FBXL12 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 FBXL12 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 FBXL12 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FBXL12 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 FBXL12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FBXL12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FBXL12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FBXL12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FBXL12 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
FBXL12 CDKN1C 25361965 interaction type N/A PTMCode2
CDKN1C FBXL12 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GSTP1 FBXL12 25348397 N/A physical interaction ComPPI
SKP1 FBXL12 18660753 24234451 25348397 27705803 association,physical association pull down,physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach ComPPI,IntAct
HSP90AB1 FBXL12 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SMAD1 FBXL12 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SLA FBXL12 25348397 N/A physical interaction ComPPI
JUN FBXL12 25348397 N/A physical interaction ComPPI
RBX1 FBXL12 18660753 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
HSP90AA1 FBXL12 25348397 N/A physical interaction ComPPI
RNH1 FBXL12 25348397 N/A physical interaction ComPPI
CDKN1C FBXL12 14525934 18660753 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
APOE FBXL12 25348397 N/A physical interaction ComPPI
PSEN2 FBXL12 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CUL1 FBXL12 18660753 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
ANXA2 FBXL12 25348397 N/A physical interaction ComPPI
COPS6 FBXL12 25348397 N/A physical interaction ComPPI
UBE2D3 FBXL12 25348397 N/A physical interaction ComPPI
CDC37 FBXL12 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAST1 FBXL12 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CAPN2 FBXL12 25348397 N/A physical interaction ComPPI
ECSIT FBXL12 25348397 N/A physical interaction ComPPI
DOCK8 FBXL12 25348397 N/A physical interaction ComPPI
CAPN1 FBXL12 25348397 N/A physical interaction ComPPI
RCN1 FBXL12 25348397 N/A physical interaction ComPPI
LNX1 FBXL12 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRAME FBXL12 25348397 N/A physical interaction ComPPI
STYX FBXL12 25348397 N/A physical interaction ComPPI
PSEN1 FBXL12 25348397 N/A physical interaction ComPPI
FBXL12 FXYD3 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FBXL12 RNF32 21163940 24234451 25348397 physical association pull down,physical interaction,two hybrid array ComPPI,IntAct
FBXL12 A2M 25348397 N/A physical interaction ComPPI
FBXL12 HSP90AA2P 25348397 N/A physical interaction ComPPI
FBXL12 ALDH3A1 25348397 N/A physical interaction ComPPI
FBXL12 ALDH3A2 25348397 N/A physical interaction ComPPI
FBXL12 ANXA2P2 25348397 N/A physical interaction ComPPI
FBXL12 HGH1 25348397 N/A physical interaction ComPPI
FBXL12 CBWD3 25348397 N/A physical interaction ComPPI
FBXL12 TTC27 25348397 N/A physical interaction ComPPI
FBXL12 ASTN2 25348397 N/A physical interaction ComPPI
FBXL12 ALDH3B1 25348397 N/A physical interaction ComPPI
FBXL12 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FBXL12 TGFBR1 14525934 15761153 N/A experimental interaction detection HPRD

Visualization