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GENE：INTS5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol INTS5
FullNmae integrator complex subunit 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29352
EnsembleID ENSG00000185085
Uniprot Q6P9B9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
INTS5 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
INTS5 GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0016020,GO:0016180,GO:0016180,GO:0031965,GO:0032039,GO:0032039,GO:0032039,GO:0034243,GO:0034472

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 INTS5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 INTS5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 INTS5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 INTS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 INTS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 INTS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 INTS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 INTS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS INTS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A INTS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 INTS5 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000AA464 INTS5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE INTS5 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
KRTAP10-8 INTS5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POLR2L INTS5 25348397 N/A physical interaction ComPPI
TOMM22 INTS5 25348397 N/A physical interaction ComPPI
PPP2R1A INTS5 24234451 25348397 28330616 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CLU INTS5 25348397 N/A physical interaction ComPPI
NTRK1 INTS5 25348397 N/A physical interaction ComPPI
PPP2CB INTS5 25348397 N/A physical interaction ComPPI
PPP2CA INTS5 24234451 25348397 26496610 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
TNF INTS5 25348397 N/A physical interaction ComPPI
CD70 INTS5 25348397 N/A physical interaction ComPPI
POLR2E INTS5 25348397 N/A physical interaction ComPPI
POLR2A INTS5 25348397 N/A physical interaction ComPPI
HLA-B INTS5 25348397 N/A physical interaction ComPPI
CD79B INTS5 25348397 N/A physical interaction ComPPI
PPP2R1B INTS5 25348397 N/A physical interaction ComPPI
POLR2J INTS5 25348397 N/A physical interaction ComPPI
TGOLN2 INTS5 25348397 N/A physical interaction ComPPI
POLR2C INTS5 25348397 N/A physical interaction ComPPI
POLR2G INTS5 25348397 N/A physical interaction ComPPI
CNOT1 INTS5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2D INTS5 25348397 N/A physical interaction ComPPI
POLR2H INTS5 25348397 N/A physical interaction ComPPI
POLR2B INTS5 25348397 N/A physical interaction ComPPI
CHRM4 INTS5 25348397 N/A physical interaction ComPPI
BSG INTS5 25348397 N/A physical interaction ComPPI
E2F3 INTS5 22157815 24234451 25348397 association pull down ComPPI,IntAct
INTS3 INTS5 25348397 N/A physical interaction ComPPI
INTS2 INTS5 25348397 N/A physical interaction ComPPI
INTS5 INTS6 25348397 N/A physical interaction ComPPI
INTS5 NABP2 25348397 N/A physical interaction ComPPI
INTS5 ZNF687 25348397 N/A physical interaction ComPPI
MKI67 INTS5 24234451 26949251 association anti tag coimmunoprecipitation IntAct

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