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GENE：RNF146

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RNF146
FullNmae ring finger protein 146
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21336
EnsembleID ENSG00000118518
Uniprot Q9NTX7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RNF146 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNF146 parthanatos 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
RNF146 entotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNF146 entotic_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RNF146 GO:0004842,GO:0004842,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0006511,GO:0006511,GO:0008270,GO:0016055,GO:0051865,GO:0061630,GO:0070936,GO:0072572,GO:0072572,GO:0090263,GO:0090263

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF146 TNKS2 19759537 21478859 21799911 22274711 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR RNF146 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RNF146 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 RNF146 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RNF146 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RNF146 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RNF146 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RNF146 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RNF146 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RNF146 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA RNF146 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000367985 RNF146 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 RNF146 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 RNF146 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 RNF146 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 RNF146 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BCD9C RNF146 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 RNF146 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 RNF146 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 RNF146 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000A057E RNF146 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E RNF146 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000057A7C RNF146 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 RNF146 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TUBB RNF146 25348397 N/A physical interaction ComPPI
UBE2D1 RNF146 25348397 N/A physical interaction ComPPI
KASH5 RNF146 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CETN2 RNF146 25348397 N/A physical interaction ComPPI
SH3BP2 RNF146 25348397 N/A physical interaction ComPPI
UBE2D2 RNF146 25348397 N/A physical interaction ComPPI
UBE2G2 RNF146 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
APC RNF146 25348397 N/A physical interaction ComPPI
PARP1 RNF146 25348397 N/A physical interaction ComPPI
XRCC1 RNF146 25348397 N/A physical interaction ComPPI
XRCC5 RNF146 25348397 N/A physical interaction ComPPI
PARP2 RNF146 25348397 N/A physical interaction ComPPI
AXIN2 RNF146 25348397 N/A physical interaction ComPPI
PFN2 RNF146 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
HSPA5 RNF146 25348397 N/A physical interaction ComPPI
HNRNPU RNF146 25348397 N/A physical interaction ComPPI
XRCC6 RNF146 25348397 N/A physical interaction ComPPI
BLZF1 RNF146 25348397 N/A physical interaction ComPPI
XPO1 RNF146 25348397 N/A physical interaction ComPPI
TRAF2 RNF146 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
IPO7 RNF146 25348397 N/A physical interaction ComPPI
SUPT16H RNF146 25348397 N/A physical interaction ComPPI
XPC RNF146 25348397 N/A physical interaction ComPPI
HSPA9 RNF146 25348397 N/A physical interaction ComPPI
PTEN RNF146 25348397 N/A physical interaction ComPPI
LIG3 RNF146 25348397 N/A physical interaction ComPPI
UBE2D3 RNF146 25348397 N/A physical interaction ComPPI
SSRP1 RNF146 25348397 N/A physical interaction ComPPI
TNKS RNF146 24234451 25327252 25348397 physical association anti tag coimmunoprecipitation,light scattering,molecular sieving,pull down,physical interaction ComPPI,IntAct
UBE2H RNF146 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
H1-2 RNF146 25348397 N/A physical interaction ComPPI
HLTF RNF146 25348397 N/A physical interaction ComPPI
TUBGCP4 RNF146 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF146 NCL 25348397 N/A physical interaction ComPPI
RNF146 IPO5 25348397 N/A physical interaction ComPPI
RNF146 ATP5F1A 25348397 N/A physical interaction ComPPI
RNF146 CHD1L 25348397 N/A physical interaction ComPPI
RNF146 H2AC21 25348397 N/A physical interaction ComPPI

Visualization










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