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GENE：ISOC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ISOC2
FullNmae isochorismatase domain containing 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26278
EnsembleID ENSG00000063241
Uniprot Q96AB3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ISOC2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ISOC2 GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0031648

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ISOC2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ISOC2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ISOC2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ISOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 ISOC2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00004E008F ISOC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 ISOC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000148B91 ISOC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 ISOC2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CALML3 ISOC2 25348397 N/A physical interaction ComPPI
MCM2 ISOC2 25348397 N/A physical interaction ComPPI
LSM8 ISOC2 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ENO1 ISOC2 25348397 N/A physical interaction ComPPI
GTPBP1 ISOC2 25348397 N/A physical interaction ComPPI
TGFBRAP1 ISOC2 25348397 N/A physical interaction ComPPI
PDK2 ISOC2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
INPP5A ISOC2 25348397 N/A physical interaction ComPPI
IL12RB1 ISOC2 25348397 N/A physical interaction ComPPI
MPP2 ISOC2 25348397 N/A physical interaction ComPPI
APIP ISOC2 25348397 N/A physical interaction ComPPI
ISOC2 APP 25348397 N/A physical interaction ComPPI
ISOC2 MOV10 25348397 N/A physical interaction ComPPI
ISOC2 NXF1 25348397 N/A physical interaction ComPPI
ISOC2 FH 25348397 N/A physical interaction ComPPI
ISOC2 ELP3 25348397 N/A physical interaction ComPPI
ISOC2 HBS1L 25348397 N/A physical interaction ComPPI

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