Gene Information gene info

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GENE：LAGE3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LAGE3
FullNmae L antigen family member 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26058
EnsembleID ENSG00000196976
Uniprot Q14657

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LAGE3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LAGE3 GO:0000408,GO:0000408,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0008033,GO:0008150,GO:0016604,GO:0070525

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 LAGE3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F4 LAGE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LAGE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LAGE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC LAGE3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
VPS37C LAGE3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP10-8 LAGE3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZNRD2 LAGE3 25348397 N/A physical interaction ComPPI
POP7 LAGE3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAGE3 KRT40 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LAGE3 CAND1 25348397 N/A physical interaction ComPPI
LAGE3 CUL2 25348397 N/A physical interaction ComPPI
LAGE3 TP53RK 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
LAGE3 TPRKB 25348397 N/A physical interaction ComPPI
LAGE3 ELOC 25348397 N/A physical interaction ComPPI
LAGE3 ELOB 25348397 N/A physical interaction ComPPI
LAGE3 MAGED2 25348397 N/A physical interaction ComPPI
LAGE3 PTMS 25348397 N/A physical interaction ComPPI
LAGE3 AHCYL1 25348397 N/A physical interaction ComPPI
LAGE3 TOM1L2 25348397 N/A physical interaction ComPPI
LAGE3 OGFR 25348397 N/A physical interaction ComPPI
LAGE3 RAB5B 25348397 N/A physical interaction ComPPI
LAGE3 RPAP1 25348397 N/A physical interaction ComPPI
LAGE3 USP34 25348397 N/A physical interaction ComPPI
LAGE3 PLP2 25348397 N/A physical interaction ComPPI
LAGE3 SNRPF 25348397 N/A physical interaction ComPPI
LAGE3 GINS4 25348397 N/A physical interaction ComPPI
LAGE3 RNF114 25348397 N/A physical interaction ComPPI
LAGE3 CNN2 25348397 N/A physical interaction ComPPI
LAGE3 PDE9A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LAGE3 NUP43 25348397 N/A physical interaction ComPPI
LAGE3 CCT7 25348397 N/A physical interaction ComPPI
LAGE3 EIF4A1 25348397 N/A physical interaction ComPPI
LAGE3 EIF4A2 25348397 N/A physical interaction ComPPI
LAGE3 ILF2 25348397 N/A physical interaction ComPPI
LAGE3 MCM5 25348397 N/A physical interaction ComPPI
LAGE3 NFYB 25348397 N/A physical interaction ComPPI
LAGE3 PSMD4 25348397 N/A physical interaction ComPPI
LAGE3 RPSA 25348397 N/A physical interaction ComPPI
LAGE3 USP5 25348397 N/A physical interaction ComPPI
LAGE3 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LAGE3 CCDC28B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
LAGE3 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LAGE3 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LAGE3 SQSTM1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
LAGE3 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
LAGE3 MIPOL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAGE3 PSMB9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAGE3 PLEKHJ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAGE3 TRIM23 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAGE3 TRIM27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAGE3 AKAP8L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAGE3 PNMA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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