GENE:RABGAP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RABGAP1 |
| FullNmae | RAB GTPase activating protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17155 |
| EnsembleID | ENSG00000011454 |
| Uniprot | Q9Y3P9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RABGAP1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RABGAP1 | GO:0005096,GO:0005515,GO:0005813,GO:0005829,GO:0005829,GO:0005875,GO:0007049,GO:0015631,GO:0031267,GO:0043087 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | RABGAP1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | RABGAP1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | RABGAP1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | RABGAP1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | RABGAP1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HIF1A | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | RABGAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000B59A2 | RABGAP1 | 16822819 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000009262D | RABGAP1 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000DDD35 | RABGAP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005CC20C | RABGAP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000037D7E5 | RABGAP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003883FE | RABGAP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076E54 | RABGAP1 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | RABGAP1 | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | RABGAP1 | 20371350 21572407 23446348 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | RABGAP1 | 20371350 21572407 23313552 23446348 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000202460 | RABGAP1 | 20371350 21572407 22012620 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000353492 | RABGAP1 | 21572407 23313552 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | RABGAP1 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | RABGAP1 | 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000013ABA3 | RABGAP1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000184017 | RABGAP1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B341F | RABGAP1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000330617 | RABGAP1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000148B91 | RABGAP1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CC005 | RABGAP1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002ECEE4 | RABGAP1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00002D2333 | RABGAP1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E628F | RABGAP1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CORO1A | RABGAP1 | 25348397 | N/A | physical interaction | ComPPI |
| WASHC3 | RABGAP1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB4A | RABGAP1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| HOXC4 | RABGAP1 | 25348397 | N/A | physical interaction | ComPPI |
| KIF5B | RABGAP1 | 25348397 | N/A | physical interaction | ComPPI |
| VCP | RABGAP1 | 25348397 | N/A | physical interaction | ComPPI |
| GABARAPL2 | RABGAP1 | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| MAP1LC3B | RABGAP1 | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| TWIST1 | RABGAP1 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| ITGB1 | RABGAP1 | 25348397 | N/A | pull down | ComPPI |
| NTRK1 | RABGAP1 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | RABGAP1 | 12606711 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| HNRNPL | RABGAP1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB6A | RABGAP1 | 10202141 11071909 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD,OmniPath |
| RABGAP1 | RAB6B | 10893188 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| RABGAP1 | CARM1 | 14525934 17124247 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| RABGAP1 | GABARAPL1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| RABGAP1 | RABGAP1L | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | RABGAP1L | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RABGAP1 | DISC1 | 17043677 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| RABGAP1 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | MAP1LC3A | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | COPE | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | COPG1 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | SENP1 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | SENP5 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | TEX35 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | LIMS1 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | KIR2DL3 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | KIR2DS2 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | TUFT1 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | WIPI2 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | ORC2 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | STAT3 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,validated two hybrid | ComPPI,IntAct |
| RABGAP1 | VIPR2 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | TRIM11 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | GGA1 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | CD79B | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | DLK2 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | PACC1 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | MANSC1 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | TSKS | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | ITGB7 | 12606711 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| RABGAP1 | ARF6 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| RABGAP1 | GABARAP | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| RABGAP1 | MAP1LC3C | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| RABGAP1 | TP53 | 22653443 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| RABGAP1 | RAB11A | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| CCDC68 | RABGAP1 | 25348397 | N/A | physical interaction | ComPPI |
| RABGAP1 | RABGAP1 | 20562859 24234451 | physical association | anti tag coimmunoprecipitation | IntAct |
