Gene Information gene info

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GENE：RRAGD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RRAGD
FullNmae Ras related GTP binding D
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19903
EnsembleID ENSG00000025039
Uniprot Q9NQL2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RRAGD autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RRAGD autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RRAGD autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RRAGD GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005764,GO:0005764,GO:0005765,GO:0005813,GO:0005829,GO:0008104,GO:0009267,GO:0010507,GO:0019003,GO:0019003,GO:0032008,GO:0043231,GO:0046982,GO:0051020,GO:0060090,GO:0071230,GO:0071233,GO:1904263,GO:1990131,GO:1990253

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RRAGD hsa:58528 path:hsa04140 Autophagy - animal - Homo sapiens (human)
RRAGD hsa:58528 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
RRAGD hsa:58528 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RRAGB RRAGD 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB
RPTOR RRAGD 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 RRAGD 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 RRAGD 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 RRAGD 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 RRAGD 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RRAGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RRAGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RRAGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RRAGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RRAGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RRAGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RRAGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RRAGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002152A8 RRAGD 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00005651EE RRAGD 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000183BED RRAGD 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA RRAGD 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 RRAGD 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001F5B39 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 RRAGD 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE RRAGD 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 RRAGD 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA RRAGD 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 RRAGD 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 RRAGD 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 RRAGD 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 RRAGD 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 RRAGD 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RRAGD RRAGA 25361965 interaction type N/A PTMCode2
RRAGA RRAGD 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LAMTOR4 RRAGD 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
CHST15 RRAGD 11073942 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LAMTOR3 RRAGD 20381137 24234451 25348397 25561175 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TSC2 RRAGD 25348397 N/A physical interaction ComPPI
MTOR RRAGD 25348397 N/A physical interaction ComPPI
LAMTOR2 RRAGD 20381137 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPTOR RRAGD 22424946 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGC RRAGD 25348397 N/A physical interaction ComPPI
RRAGB RRAGD 11073942 14525934 20381137 22424946 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RRAGD NOL8 14525934 14660641 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RRAGD RRAGA 11073942 22424946 24234451 25348397 25561175 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
RRAGD LARS1 22424946 24234451 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct
RRAGD LAMTOR1 20381137 22424946 24234451 25348397 25561175 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGD TRIM16 25348397 N/A physical interaction ComPPI
RRAGD SLC38A9 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
RRAGD LAMTOR5 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
RRAGD HSPA5 24234451 30021884 physical association cross-linking study IntAct
RRAGD RPTOR 18497260 20006481 22424946 24337580 27898060 inhibition,stimulant N/A OmniPath
RRAGD RRAGB 11073942 18497260 20381137 22424946 24337580 27898060 N/A N/A OmniPath

Visualization










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