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GENE：SPTSSA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPTSSA
FullNmae serine palmitoyltransferase small subunit A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20361
EnsembleID ENSG00000165389
Uniprot Q969W0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPTSSA autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPTSSA GO:0004758,GO:0004758,GO:0005515,GO:0005783,GO:0005789,GO:0005789,GO:0008104,GO:0017059,GO:0017059,GO:0017059,GO:0030148,GO:0046512,GO:0046513,GO:0046513

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SPTSSA hsa:171546 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 SPTSSA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SPTSSA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SPTSSA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPTSSA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SPTSSA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SPTSSA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPTSSA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SPTSSA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SPTSSA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000170CF4 SPTSSA 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000031602A SPTSSA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC SPTSSA 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 SPTSSA 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD SPTSSA 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 SPTSSA 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000052E1A6 SPTSSA 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD SPTSSA 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A SPTSSA 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF SPTSSA 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000F7766 SPTSSA 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 SPTSSA 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HNRNPL SPTSSA 25348397 N/A physical interaction ComPPI
TRIM25 SPTSSA 25348397 N/A physical interaction ComPPI
ELAVL1 SPTSSA 25348397 N/A physical interaction ComPPI
TUBB4A SPTSSA 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SPTLC1 SPTSSA 19416851 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
TUBB3 SPTSSA 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
SPTSSA MBOAT7 23510452 25348397 27898060 N/A physical interaction ComPPI,OmniPath

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