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GENE：SRSF8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SRSF8
FullNmae serine and arginine rich splicing factor 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16988
EnsembleID ENSG00000263465
Uniprot Q9BRL6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SRSF8 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SRSF8 GO:0000398,GO:0003723,GO:0003723,GO:0005515,GO:0005654,GO:0005654,GO:0005829,GO:0016607,GO:0016607

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SRSF8 hsa:10929 path:hsa03040 Spliceosome - Homo sapiens (human)
SRSF8 hsa:10929 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SRSF8 SUZ12 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
SRPK1 SRSF8 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB
SRPK2 SRSF8 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SRSF8 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 SRSF8 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SRSF8 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SNIP1 SRSF8 25348397 N/A physical interaction ComPPI
SNRNP70 SRSF8 25348397 N/A physical interaction ComPPI
CD81 SRSF8 25348397 N/A physical interaction ComPPI
YWHAZ SRSF8 25348397 N/A physical interaction ComPPI
SREK1 SRSF8 14525934 14559993 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
CLK2 SRSF8 25348397 N/A physical interaction ComPPI
NXF2 SRSF8 25348397 N/A physical interaction ComPPI
ATM SRSF8 25348397 N/A physical interaction ComPPI
SRPK1 SRSF8 23602568 24234451 25348397 phosphorylation reaction,association physical interaction,protein kinase assay,tandem affinity purification ComPPI,IntAct
YWHAH SRSF8 25348397 N/A physical interaction ComPPI
SFN SRSF8 25348397 N/A physical interaction ComPPI
EED SRSF8 25348397 N/A physical interaction ComPPI
MECP2 SRSF8 25348397 N/A physical interaction ComPPI
ELAVL1 SRSF8 25348397 N/A physical interaction ComPPI
SRPK2 SRSF8 23602568 24234451 25348397 phosphorylation reaction,association physical interaction,protein kinase assay,tandem affinity purification ComPPI,IntAct
MAGOH SRSF8 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRA2A SRSF8 25348397 N/A physical interaction ComPPI
CLK3 SRSF8 25348397 N/A physical interaction ComPPI
SRSF8 APP 25348397 N/A physical interaction ComPPI
SRSF8 PAN2 25348397 N/A physical interaction ComPPI
SRSF8 IGSF8 25348397 N/A physical interaction ComPPI
SRSF8 SUZ12 25348397 N/A physical interaction ComPPI
SRSF8 LUC7L 25348397 N/A physical interaction ComPPI
SRSF8 LUC7L2 25348397 N/A physical interaction ComPPI
SRSF8 CLCN2 25348397 N/A physical interaction ComPPI
SRSF8 CCDC88A 25348397 N/A physical interaction ComPPI
SRSF8 ZC3H18 25348397 N/A physical interaction ComPPI
SRSF8 NKAPD1 25348397 N/A physical interaction ComPPI
SRSF8 ELAVL2 25348397 N/A physical interaction ComPPI
SRSF8 PIP4K2A 25348397 N/A physical interaction ComPPI
EIF4A3 SRSF8 23084401 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
IL36RN SRSF8 25348397 N/A physical interaction ComPPI
DDX41 SRSF8 24234451 25348397 25920683 association anti tag coimmunoprecipitation ComPPI,IntAct
MKI67 SRSF8 24234451 26949251 association anti tag coimmunoprecipitation IntAct

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