GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
TBC1D2 |
| FullNmae |
TBC1 domain family member 2 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:18026 |
| EnsembleID |
ENSG00000095383 |
| Uniprot |
Q9BYX2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| TBC1D2 |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| TBC1D2 |
GO:0005096,GO:0005096,GO:0005515,GO:0005654,GO:0005829,GO:0005886,GO:0030054,GO:0031410,GO:0043547,GO:0045296,GO:0070161,GO:0090630 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| EGR1 |
TBC1D2 |
19374776
23180781
|
physical association |
anti tag coimmunoprecipitation |
InnateDB |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| AR |
TBC1D2 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| ETS1 |
TBC1D2 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| GATA1 |
TBC1D2 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
TBC1D2 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
TBC1D2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
TBC1D2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
TBC1D2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F4 |
TBC1D2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
TBC1D2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
TBC1D2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
TBC1D2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
TBC1D2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
TBC1D2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS0000508C13 |
TBC1D2 |
N/A
15685193
|
rna interference,inhibition |
array technology |
miRSponge |
| URS0000508C13 |
TBC1D2 |
15685193
25416803
|
mrna cleavage,inhibition |
array technology,array technology,experimental interaction detection |
TarBase |
| URS00002075FA |
TBC1D2 |
23285084
25416803
|
mrna cleavage,inhibition |
western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| CDC42 |
TBC1D2 |
25348397
|
N/A |
two hybrid |
ComPPI |
| CCND1 |
TBC1D2 |
24234451
24412244
25348397
|
physical association |
two hybrid,two hybrid array |
ComPPI,IntAct |
| BUB1 |
TBC1D2 |
24234451
24412244
25348397
|
physical association |
two hybrid,two hybrid array |
ComPPI,IntAct |
| DNM1 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TRIP10 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| AP1B1 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| POLD1 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MAP1LC3A |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| AURKA |
TBC1D2 |
24234451
24412244
25348397
|
physical association |
two hybrid,two hybrid array |
ComPPI,IntAct |
| ILF2 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TBC1D4 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TSEN2 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CPSF6 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GABARAPL1 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| DCC |
TBC1D2 |
24234451
24412244
25348397
|
physical association |
two hybrid,two hybrid array |
ComPPI,IntAct |
| INTS9 |
TBC1D2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MLH3 |
TBC1D2 |
24234451
24412244
25348397
|
physical association |
two hybrid,two hybrid array |
ComPPI,IntAct |
| TBC1D2 |
PDGFRL |
24234451
24412244
25348397
|
physical association |
two hybrid,two hybrid array |
ComPPI,IntAct |
Visualization