GENE：TBC1D2B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TBC1D2B |
| FullNmae | TBC1 domain family member 2B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29183 |
| EnsembleID | ENSG00000167202 |
| Uniprot | Q9UPU7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TBC1D2B | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TBC1D2B | GO:0005096,GO:0005515,GO:0005769,GO:0005829,GO:0006897,GO:0090630 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TBC1D2B | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | TBC1D2B | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | TBC1D2B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | TBC1D2B | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | TBC1D2B | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TBC1D2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003ABC4 | TBC1D2B | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00005651EE | TBC1D2B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000458AD2 | TBC1D2B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000192A75 | TBC1D2B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | TBC1D2B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000057FDB8 | TBC1D2B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000013ABA3 | TBC1D2B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B0F6 | TBC1D2B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | TBC1D2B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PSMC3 | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| GABARAPL2 | TBC1D2B | 20562859 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,pull down | ComPPI,IntAct |
| MAP1LC3B | TBC1D2B | 20562859 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,pull down | ComPPI,IntAct |
| PAK5 | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| ECT2 | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| CAV3 | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| ALOX5 | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| GABARAP | TBC1D2B | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| MAP1LC3A | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| S100A6 | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| GABARAPL1 | TBC1D2B | 20562859 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| PTCD3 | TBC1D2B | 25348397 | N/A | physical interaction | ComPPI |
| OFD1 | TBC1D2B | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| MAP1LC3C | TBC1D2B | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |