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GENE：UQCR10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UQCR10
FullNmae ubiquinol-cytochrome c reductase, complex III subunit X
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30863
EnsembleID ENSG00000184076
Uniprot Q9UDW1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UQCR10 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UQCR10 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
UQCR10 GO:0005515,GO:0005743,GO:0005743,GO:0005750,GO:0005750,GO:0006122,GO:0006122,GO:0008121,GO:0045333,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UQCR10 hsa:29796 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa01100 Metabolic pathways - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa04260 Cardiac muscle contraction - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa04714 Thermogenesis - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa05010 Alzheimer disease - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa05012 Parkinson disease - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa05016 Huntington disease - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa05020 Prion disease - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
UQCR10 hsa:29796 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR UQCR10 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 UQCR10 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 UQCR10 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 UQCR10 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA UQCR10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UQCR10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UQCR10 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003FD55 UQCR10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 UQCR10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 UQCR10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 UQCR10 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 UQCR10 22291592 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CYC1 UQCR10 25361965 interaction type N/A PTMCode2
UQCR10 CYC1 25361965 interaction type N/A PTMCode2
UQCRC1 UQCR10 25361965 interaction type N/A PTMCode2
UQCR10 UQCRC1 25361965 interaction type N/A PTMCode2
UQCRH UQCR10 25361965 interaction type N/A PTMCode2
UQCR10 UQCRH 25361965 interaction type N/A PTMCode2
UQCRFS1 UQCR10 25361965 interaction type N/A PTMCode2
UQCR10 UQCRFS1 25361965 interaction type N/A PTMCode2
UQCR10 UQCRQ 25361965 interaction type N/A PTMCode2
UQCRQ UQCR10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
S100A4 UQCR10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMMDC1 UQCR10 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KPNB1 UQCR10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PEX19 UQCR10 25348397 N/A physical interaction ComPPI
NIT1 UQCR10 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GPM6A UQCR10 25348397 N/A physical interaction ComPPI
RAB11A UQCR10 25348397 N/A physical interaction ComPPI
UQCRC1 UQCR10 19688755 24234451 25348397 physical association blue native page ComPPI,IntAct
CLPP UQCR10 24234451 25348397 26058080 association proximity-dependent biotin identification ComPPI,IntAct
HNRNPM UQCR10 25348397 N/A physical interaction ComPPI
UQCRB UQCR10 25348397 N/A physical interaction ComPPI
CYC1 UQCR10 25348397 N/A physical interaction ComPPI
ERBB3 UQCR10 25348397 N/A physical interaction ComPPI
NDUFA9 UQCR10 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MOV10 UQCR10 25348397 N/A physical interaction ComPPI
NDUFS3 UQCR10 25348397 N/A physical interaction ComPPI
CYSTM1 UQCR10 25348397 N/A physical interaction ComPPI
UQCR10 NDUFA11 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UQCR10 NMES1 25348397 N/A physical interaction ComPPI
UQCR10 NDUFAF8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
UQCR10 OLFML3 24234451 30021884 physical association cross-linking study IntAct

Visualization










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