Gene Information gene info

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GENE：WDR5B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WDR5B
FullNmae WD repeat domain 5B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17826
EnsembleID ENSG00000196981
Uniprot Q86VZ2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WDR5B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
WDR5B GO:0042393,GO:0048188,GO:0051568

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
WDR5B hsa:54554 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)
WDR5B hsa:54554 path:hsa04934 Cushing syndrome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 WDR5B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 WDR5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS WDR5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 WDR5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000451A1 WDR5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 WDR5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 WDR5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 WDR5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 WDR5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 WDR5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A WDR5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D WDR5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 WDR5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B WDR5B 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000032835F WDR5B 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 WDR5B 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 WDR5B 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 WDR5B 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 WDR5B 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 WDR5B 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KMT2D WDR5B 16603732 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ASH2L WDR5B 16603732 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RBBP5 WDR5B 16603732 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL4B WDR5B 25348397 N/A physical interaction ComPPI
CUL4A WDR5B 17041588 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TCP1 WDR5B 25348397 N/A physical interaction ComPPI
CCT7 WDR5B 25348397 N/A physical interaction ComPPI
DDB1 WDR5B 17041588 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ESR1 WDR5B 16603732 24234451 25348397 association pull down ComPPI,IntAct
CLTCL1 WDR5B 25348397 N/A physical interaction ComPPI
WDR5 WDR5B 25348397 N/A physical interaction ComPPI
RRP12 WDR5B 25348397 N/A physical interaction ComPPI
CCT4 WDR5B 25348397 N/A physical interaction ComPPI
CCT2 WDR5B 25348397 N/A physical interaction ComPPI
CCT6A WDR5B 25348397 N/A physical interaction ComPPI
RNF220 WDR5B 25348397 N/A physical interaction ComPPI
CCT3 WDR5B 25348397 N/A physical interaction ComPPI
SNRNP27 WDR5B 25348397 N/A physical interaction ComPPI
ZNRF2 WDR5B 25348397 N/A physical interaction ComPPI

Visualization










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