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GENE：ARHGEF3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARHGEF3
FullNmae Rho guanine nucleotide exchange factor 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:683
EnsembleID ENSG00000163947
Uniprot Q9NR81

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARHGEF3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARHGEF3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARHGEF3 GO:0005085,GO:0005515,GO:0005829,GO:0007266,GO:0035025,GO:0051056

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TRIM23 ARHGEF3 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR ARHGEF3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 ARHGEF3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 ARHGEF3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ARHGEF3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 ARHGEF3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 ARHGEF3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ARHGEF3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ARHGEF3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ARHGEF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 ARHGEF3 N/A 15685193 rna interference,inhibition array technology miRSponge
URS0000508C13 ARHGEF3 15685193 25416803 mrna cleavage,inhibition array technology,array technology,experimental interaction detection TarBase
URS0000237AF9 ARHGEF3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00004E008F ARHGEF3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007F792 ARHGEF3 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A ARHGEF3 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00005E6F45 ARHGEF3 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 ARHGEF3 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E ARHGEF3 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 ARHGEF3 22291592 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RHOA ARHGEF3 25361965 interaction type N/A PTMCode2
ARHGEF3 RHOA 25361965 interaction type N/A PTMCode2
CDC42 ARHGEF3 25361965 interaction type N/A PTMCode2
ARHGEF3 CDC42 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC42 ARHGEF3 25348397 N/A two hybrid ComPPI
PBX4 ARHGEF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PICK1 ARHGEF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RHOB ARHGEF3 12221096 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ARHGEF3 TRIM23 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ARHGEF3 TRIM27 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ARHGEF3 CEP70 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ARHGEF3 SHMT2 25348397 N/A physical interaction ComPPI
ARHGEF3 NXF1 25348397 N/A physical interaction ComPPI
ARHGEF3 XPO1 25348397 N/A physical interaction ComPPI
ARHGEF3 TERF1 25348397 N/A two hybrid ComPPI
ARHGEF3 HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RHOA ARHGEF3 12221096 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD

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