Gene Information gene info

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GENE：FXYD2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FXYD2
FullNmae FXYD domain containing ion transport regulator 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4026
EnsembleID ENSG00000137731
Uniprot P54710

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FXYD2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FXYD2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FXYD2 GO:0001671,GO:0005886,GO:0005890,GO:0005890,GO:0006883,GO:0010248,GO:0017080,GO:0030007,GO:0030674,GO:0036376,GO:0036376,GO:0055085,GO:0070062,GO:1902600,GO:1903408,GO:1990573,GO:1990573,GO:2000649

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FXYD2 hsa:486 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04260 Cardiac muscle contraction - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04911 Insulin secretion - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04918 Thyroid hormone synthesis - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04964 Proximal tubule bicarbonate reclamation - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04970 Salivary secretion - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04972 Pancreatic secretion - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04974 Protein digestion and absorption - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04976 Bile secretion - Homo sapiens (human)
FXYD2 hsa:486 path:hsa04978 Mineral absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 FXYD2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 FXYD2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 FXYD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FXYD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FXYD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FXYD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FXYD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FXYD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 FXYD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF1B FXYD2 24204001 trascriptional regulation,stimulation inferred by curator TFlink
PCBD1 FXYD2 24204001 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 FXYD2 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS000075A513 FXYD2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 FXYD2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA FXYD2 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATP1A1 FXYD2 11832419 25348397 27898060 N/A in vivo ComPPI,OmniPath

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