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GENE：ADCY7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ADCY7
FullNmae adenylate cyclase 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:238
EnsembleID ENSG00000121281
Uniprot P51828

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ADCY7 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ADCY7 GO:0002819,GO:0004016,GO:0004016,GO:0004016,GO:0005524,GO:0005886,GO:0005886,GO:0006171,GO:0006171,GO:0007189,GO:0007193,GO:0016020,GO:0035556,GO:0046872,GO:0060135,GO:0071285,GO:0071361,GO:1900016

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ADCY7 hsa:113 path:hsa00230 Purine metabolism - Homo sapiens (human)
ADCY7 hsa:113 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ADCY7 hsa:113 path:hsa01522 Endocrine resistance - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04114 Oocyte meiosis - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04540 Gap junction - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04611 Platelet activation - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04713 Circadian entrainment - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04714 Thermogenesis - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04724 Glutamatergic synapse - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04725 Cholinergic synapse - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04727 GABAergic synapse - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04911 Insulin secretion - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04912 GnRH signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04913 Ovarian steroidogenesis - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04915 Estrogen signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04916 Melanogenesis - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04918 Thyroid hormone synthesis - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04927 Cortisol synthesis and secretion - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04934 Cushing syndrome - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04935 Growth hormone synthesis, secretion and action - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04970 Salivary secretion - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04971 Gastric acid secretion - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04972 Pancreatic secretion - Homo sapiens (human)
ADCY7 hsa:113 path:hsa04976 Bile secretion - Homo sapiens (human)
ADCY7 hsa:113 path:hsa05032 Morphine addiction - Homo sapiens (human)
ADCY7 hsa:113 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
ADCY7 hsa:113 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
ADCY7 hsa:113 path:hsa05200 Pathways in cancer - Homo sapiens (human)
ADCY7 hsa:113 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
ADCY7 hsa:113 path:hsa05414 Dilated cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ADCY7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ADCY7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ADCY7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ADCY7 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ADCY7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ADCY7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ADCY7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ADCY7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ADCY7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ADCY7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ADCY7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ADCY7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ADCY7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 ADCY7 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EC1BE ADCY7 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000036AFF1 ADCY7 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC ADCY7 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 ADCY7 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 ADCY7 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA ADCY7 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 ADCY7 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ADCY7 PRKCD 25361965 interaction type N/A PTMCode2
PRKCD ADCY7 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PRKCD ADCY7 12454008 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PLSCR1 ADCY7 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
XRCC6 ADCY7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ADCY7 BUD31 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
H2BC9 ADCY7 24234451 30021884 physical association cross-linking study IntAct
PRKCE ADCY7 17185372 27898060 stimulant N/A OmniPath
PRKCD ADCY7 12454008 17185372 27898060 stimulant N/A OmniPath

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