GENE：ATP1B3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ATP1B3 |
| FullNmae | ATPase Na+/K+ transporting subunit beta 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:806 |
| EnsembleID | ENSG00000069849 |
| Uniprot | P54709 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ATP1B3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ATP1B3 | GO:0001671,GO:0001671,GO:0005515,GO:0005886,GO:0005886,GO:0005890,GO:0005890,GO:0005890,GO:0006883,GO:0006883,GO:0016323,GO:0016324,GO:0030007,GO:0030007,GO:0030674,GO:0030674,GO:0032781,GO:0035725,GO:0036126,GO:0036376,GO:0036376,GO:0042470,GO:0050821,GO:0051117,GO:0070062,GO:0071805,GO:0072659,GO:0086009,GO:1901018,GO:1903278,GO:1903288,GO:1990573,GO:1990573 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ATP1B3 | hsa:483 | path:hsa04022 | cGMP-PKG signaling pathway - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04024 | cAMP signaling pathway - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04260 | Cardiac muscle contraction - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04261 | Adrenergic signaling in cardiomyocytes - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04911 | Insulin secretion - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04918 | Thyroid hormone synthesis - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04919 | Thyroid hormone signaling pathway - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04925 | Aldosterone synthesis and secretion - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04960 | Aldosterone-regulated sodium reabsorption - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04961 | Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04964 | Proximal tubule bicarbonate reclamation - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04970 | Salivary secretion - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04971 | Gastric acid secretion - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04972 | Pancreatic secretion - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04973 | Carbohydrate digestion and absorption - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04974 | Protein digestion and absorption - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04976 | Bile secretion - Homo sapiens (human) |
| ATP1B3 | hsa:483 | path:hsa04978 | Mineral absorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ATP1B3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | ATP1B3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ATP1B3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ATP1B3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | ATP1B3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ATP1B3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ATP1B3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ATP1B3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | ATP1B3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ATP1B3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ATP1B3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000512C88 | ATP1B3 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000021D7C8 | ATP1B3 | 23313552 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS00001A405B | ATP1B3 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000E1E9E | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E2232 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031B6ED | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018D2BE | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E949 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000346991 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000070CD2 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032D69B | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F3336 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F74F1 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000072E4C | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018E72A | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AEA5 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B7450 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031F6C2 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000033EBB8 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000100748 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5BAA | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EE123 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CCBB9 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023F8DA | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000284586 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5E03 | ATP1B3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ANP32B | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB5 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| SEMA4C | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| ITGA7 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RPL10 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| GRN | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| PAXIP1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| DLD | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| CANX | ATP1B3 | 24234451 25348397 29568061 | association | pull down | ComPPI,IntAct |
| SCARB1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| TM9SF2 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| MAPK6 | ATP1B3 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| VDAC1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| EWSR1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RAB1A | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| QARS1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| USP4 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| UPF2 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| VDAC2 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RPLP2 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1A1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| ADRB2 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| TUBA1A | ATP1B3 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| EFNB1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| TGFBR3 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RTN4 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RAB1B | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| BARD1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| BRCA1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| EEF2 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RPS9 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| TOMM40 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| OGDH | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| ITGA5 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| UQCRB | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| BAALC | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| PSMD6 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| CYC1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RPL22 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| TMEM259 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RPL17 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RPL26 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| VDAC3 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| MYH2 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| PTP4A3 | ATP1B3 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HMGCR | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| MTCH1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1A3 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| NDUFS1 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| BACE2 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RPS19 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| NDUFA9 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| RPL35 | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| ATP5PB | ATP1B3 | 25348397 | N/A | physical interaction | ComPPI |
| SFXN1 | ATP1B3 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| ATP1B3 | HLA-C | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | FADS2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | RTN2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | ACAT1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | NDUFA12 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | NDUFA2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | NDUFA8 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | NDUFB7 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | NDUFS3 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | NDUFS5 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | RPS8 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B3 | TMEM98 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ATP1B3 | PLEKHA7 | 24234451 25348397 28877994 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |