GENE：CENPS
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CENPS |
| FullNmae | centromere protein S |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:23163 |
| EnsembleID | ENSG00000175279 |
| Uniprot | Q8N2Z9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CENPS | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CENPS | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CENPS | GO:0000712,GO:0000712,GO:0000785,GO:0000939,GO:0003677,GO:0003682,GO:0003682,GO:0003690,GO:0005515,GO:0005634,GO:0005654,GO:0005829,GO:0006281,GO:0006974,GO:0006974,GO:0007059,GO:0031297,GO:0031297,GO:0031398,GO:0036297,GO:0043240,GO:0043240,GO:0046982,GO:0051301,GO:0071821,GO:0071821,GO:0071821 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CENPS | hsa:378708 | path:hsa03460 | Fanconi anemia pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | CENPS | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ESR1 | CENPS | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | CENPS | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | CENPS | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | CENPS | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | CENPS | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | CENPS | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CENPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CENPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CENPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CENPK | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| RPA1 | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| BLM | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| RPA2 | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FANCC | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FANCE | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FANCF | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| ESR1 | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| TOP3A | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| CENPU | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FANCL | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FANCB | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FAAP24 | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FANCM | CENPS | 23886707 24234451 25348397 | physical association | molecular sieving,physical interaction,x ray scattering | ComPPI,IntAct |
| HOMEZ | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| APP | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FANCA | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FANCG | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| RMI1 | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FAAP100 | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| CENPS | RMI2 | 25348397 | N/A | physical interaction | ComPPI |
| CENPS | FAAP20 | 25348397 | N/A | physical interaction | ComPPI |
| CENPS | CENPW | 22304917 24234451 25348397 | physical association | molecular sieving | ComPPI,IntAct |