GENE:CSTF2T
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CSTF2T |
| FullNmae | cleavage stimulation factor subunit 2 tau variant |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17086 |
| EnsembleID | ENSG00000177613 |
| Uniprot | Q9H0L4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CSTF2T | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CSTF2T | GO:0003723,GO:0003729,GO:0005515,GO:0005654,GO:0005654,GO:0005847,GO:0031124,GO:0043231 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CSTF2T | hsa:23283 | path:hsa03015 | mRNA surveillance pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | CSTF2T | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | CSTF2T | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| YBX1 | CSTF2T | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CSTF2T | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | CSTF2T | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000521626 | CSTF2T | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000028BB8 | CSTF2T | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000170CF4 | CSTF2T | 20371350 21572407 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS0000031E12 | CSTF2T | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000153377 | CSTF2T | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045E0EC | CSTF2T | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EB9FC | CSTF2T | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000209F04 | CSTF2T | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000204177 | CSTF2T | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A5E54 | CSTF2T | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D5659 | CSTF2T | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000759F6E | CSTF2T | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | CSTF2T | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003E1A9 | CSTF2T | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C308D | CSTF2T | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000157026 | CSTF2T | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GOLGA2 | CSTF2T | 21516116 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| CSTF2 | CSTF2T | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | UBQLN1 | 14525934 16189514 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
| CSTF2T | CPSF2 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | CPSF1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | CSTF3 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | HGS | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CSTF2T | FBXW11 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | CSTF1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | XPO1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | FIP1L1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSTF2T | EWSR1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | MYO1C | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSTF2T | MAPK3 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSTF2T | CPSF3 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSTF2T | SYMPK | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | BIRC2 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | CLINT1 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | FANCG | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | RFX5 | 25348397 | N/A | physical interaction | ComPPI |
| CSTF2T | CTDSP1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CSTF2T | ATP23 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CSTF2T | UBQLN2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CSTF2T | COL17A1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CSTF2T | AKAP8L | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
