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GENE：DCAF8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DCAF8
FullNmae DDB1 and CUL4 associated factor 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24891
EnsembleID ENSG00000132716
Uniprot Q5TAQ9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DCAF8 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DCAF8 GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005739,GO:0005829,GO:0016567,GO:0080008,GO:0080008

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CUL4A DCAF8 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR DCAF8 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DCAF8 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 DCAF8 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
HNF4A DCAF8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC DCAF8 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB DCAF8 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 DCAF8 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000003ABC4 DCAF8 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000009262D DCAF8 20048743 25416803 mrna cleavage,inhibition array technology TarBase
URS0000553F51 DCAF8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D DCAF8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 DCAF8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000029979D DCAF8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 DCAF8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CCBB9 DCAF8 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F DCAF8 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002ED720 DCAF8 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000036B845 DCAF8 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000A057E DCAF8 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E DCAF8 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 DCAF8 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B DCAF8 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 DCAF8 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001938D9 DCAF8 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001B968D DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003677B2 DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F DCAF8 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RBPMS DCAF8 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KPNA1 DCAF8 22500989 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
RAN DCAF8 22500989 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
MDFI DCAF8 14525934 16189514 19060904 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
COPS5 DCAF8 25348397 N/A physical interaction ComPPI
KPNB1 DCAF8 22500989 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIK3R3 DCAF8 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ACTN1 DCAF8 25348397 N/A physical interaction ComPPI
PRMT1 DCAF8 23455924 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
TNS2 DCAF8 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MYC DCAF8 25348397 N/A physical interaction ComPPI
KSR2 DCAF8 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
PRMT5 DCAF8 25348397 N/A physical interaction ComPPI
STAM2 DCAF8 25348397 N/A physical interaction ComPPI
HNRNPL DCAF8 25348397 N/A physical interaction ComPPI
XPO1 DCAF8 22500989 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUV39H1 DCAF8 23455924 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
COPS2 DCAF8 25348397 N/A physical interaction ComPPI
CUL4B DCAF8 25348397 N/A physical interaction ComPPI
WDR77 DCAF8 25348397 N/A physical interaction ComPPI
MDM2 DCAF8 25348397 N/A physical interaction ComPPI
EPB41L2 DCAF8 25348397 N/A physical interaction ComPPI
CUL4A DCAF8 25348397 N/A physical interaction ComPPI
TCP1 DCAF8 25348397 N/A physical interaction ComPPI
CCT5 DCAF8 25348397 N/A physical interaction ComPPI
CCT7 DCAF8 25348397 N/A physical interaction ComPPI
RAF1 DCAF8 25348397 N/A physical interaction ComPPI
PTPN21 DCAF8 25348397 N/A physical interaction ComPPI
TUBGCP3 DCAF8 25348397 N/A physical interaction ComPPI
COPS3 DCAF8 25348397 N/A physical interaction ComPPI
COPS4 DCAF8 25348397 N/A physical interaction ComPPI
COPS6 DCAF8 25348397 N/A physical interaction ComPPI
COPS7A DCAF8 25348397 N/A physical interaction ComPPI
TFB1M DCAF8 25348397 N/A physical interaction ComPPI
DDB1 DCAF8 14525934 16949367 16964240 19295130 19966799 24234451 24500646 25348397 27898060 N/A experimental interaction detection,x-ray crystallography,physical interaction ComPPI,HPRD,IntAct,OmniPath
FBXW11 DCAF8 25348397 N/A physical interaction ComPPI
THAP1 DCAF8 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GTPBP3 DCAF8 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCT4 DCAF8 25348397 N/A physical interaction ComPPI
CCT2 DCAF8 25348397 N/A physical interaction ComPPI
PRMT8 DCAF8 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TWNK DCAF8 25348397 N/A physical interaction ComPPI
DCAF11 DCAF8 25348397 N/A physical interaction ComPPI
DCAF8 PDE7A 25348397 N/A physical interaction ComPPI
DCAF8 AMPD2 25348397 N/A physical interaction ComPPI
DCAF8 FARP1 25348397 N/A physical interaction ComPPI
DCAF8 ARHGEF26 25348397 N/A physical interaction ComPPI
DCAF8 ACAD11 25348397 N/A physical interaction ComPPI
DCAF8 EPB41L5 25348397 N/A physical interaction ComPPI
DCAF8 REXO5 25348397 N/A physical interaction ComPPI
DCAF8 DCAF8L1 25348397 N/A physical interaction ComPPI
DCAF8 CCT6B 25348397 N/A physical interaction ComPPI
DCAF8 CCT3 25348397 N/A physical interaction ComPPI
DCAF8 ZNF460 25348397 N/A physical interaction ComPPI
DCAF8 INAVA 25348397 N/A physical interaction ComPPI
DCAF8 TMCO3 25348397 N/A physical interaction ComPPI
DCAF8 GSTK1 25348397 N/A physical interaction ComPPI
DCAF8 ZNHIT2 25348397 N/A physical interaction ComPPI
DDA1 DCAF8 25348397 N/A physical interaction ComPPI
GGH DCAF8 25348397 N/A physical interaction ComPPI

Visualization










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