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GENE：FAM53C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FAM53C
FullNmae family with sequence similarity 53 member C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1336
EnsembleID ENSG00000120709
Uniprot Q9NYF3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FAM53C autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FAM53C GO:0005515,GO:0005634,GO:0006606

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 FAM53C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FAM53C 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 FAM53C 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 FAM53C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FAM53C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FAM53C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FAM53C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 FAM53C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FAM53C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FAM53C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FAM53C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 FAM53C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE FAM53C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 FAM53C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039A25B FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F FAM53C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000077DDE FAM53C 19536157 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 FAM53C 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA FAM53C 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 FAM53C 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 FAM53C 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002971AB FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000076995 FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000272A3D FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000014F13C FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002394F5 FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000486E0B FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001CE046 FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000334286 FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005CCD18 FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000061E50F FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D15B FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AD2AA FAM53C 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NCK2 FAM53C 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FAM110A FAM53C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SORBS3 FAM53C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM53C YWHAG 20936779 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FAM53C YWHAZ 25348397 N/A physical interaction ComPPI
FAM53C YWHAE 25348397 N/A physical interaction ComPPI
FAM53C DYRK1B 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
FAM53C DYRK1A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
FAM53C SFN 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FAM53C PLK1 25348397 N/A physical interaction ComPPI
FAM53C TRAF3 25348397 N/A physical interaction ComPPI
FAM53C XPO1 25348397 N/A physical interaction ComPPI
FAM53C DCAF7 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
FAM53C KSR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C EIF4E2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C SH3PXD2A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C CDC25B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C ZNF638 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C RAB3IP 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C LRFN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C SRSF12 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C USP21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C LIMA1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C GIGYF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C SIPA1L1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C KIF13B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C MAPKAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C RTKN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C HDAC4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C TIAM1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C GAB2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C AFDN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C MELK 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C PLEKHA7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C NF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C CBY1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FAM53C YWHAH 17979178 24234451 25348397 association tandem affinity purification ComPPI,IntAct
FAM53C WNK1 20936779 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FAM53C EGLN3 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00008B73E6 FAM53C 27087310 direct interaction,inhibition N/A NPInter

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