Gene Information gene info

GENE:FARSA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FARSA
FullNmae phenylalanyl-tRNA synthetase subunit alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3592
EnsembleID ENSG00000179115
Uniprot Q9Y285

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FARSA autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FARSA GO:0000049,GO:0000287,GO:0003723,GO:0004826,GO:0004826,GO:0005515,GO:0005524,GO:0005737,GO:0005737,GO:0005829,GO:0006432,GO:0006432,GO:0009328,GO:0009328,GO:0009328,GO:0016020,GO:0051290

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FARSA hsa:2193 path:hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EIF2AK2 FARSA 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
UNC93B1 FARSA 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR FARSA 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FARSA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 FARSA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 FARSA 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 FARSA 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF FARSA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F6E49 FARSA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE FARSA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 FARSA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002E728C FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000419B5A FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027F5F3 FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000045ED38 FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E FARSA 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 FARSA 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F FARSA 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATR FARSA 22135298 phosphorylation N/A PhosphoSite
FARSB FARSA 25361965 interaction type N/A PTMCode2
FARSA FARSB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAD2L2 FARSA 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
CDC42 FARSA 25348397 N/A physical interaction ComPPI
KEAP1 FARSA 25348397 N/A physical interaction ComPPI
MCM2 FARSA 25348397 N/A physical interaction ComPPI
PDCD10 FARSA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NF2 FARSA 25348397 N/A physical interaction ComPPI
JUN FARSA 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL3 FARSA 25348397 N/A physical interaction ComPPI
UBC FARSA 25348397 N/A physical interaction ComPPI
DLD FARSA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 FARSA 25348397 N/A physical interaction ComPPI
EIF2AK2 FARSA 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WWP2 FARSA 25348397 N/A physical interaction ComPPI
APOE FARSA 25348397 N/A physical interaction ComPPI
CFTR FARSA 25348397 N/A physical interaction ComPPI
MAPK6 FARSA 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
RPLP0 FARSA 25348397 N/A physical interaction ComPPI
ABI3 FARSA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CUL1 FARSA 25348397 N/A physical interaction ComPPI
EGFR FARSA 25348397 N/A physical interaction ComPPI
TDGF1 FARSA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
OGT FARSA 25348397 N/A physical interaction ComPPI
CHEK2 FARSA 23178491 24234451 25348397 association tandem affinity purification ComPPI,IntAct
WWOX FARSA 25348397 N/A physical interaction ComPPI
PSMD2 FARSA 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
USP11 FARSA 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPS1 FARSA 25348397 N/A physical interaction ComPPI
NFKB1 FARSA 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
HNRNPR FARSA 14525934 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ECSIT FARSA 21163940 24234451 25348397 physical association pull down,physical interaction,two hybrid array ComPPI,IntAct
ESR1 FARSA 25348397 N/A physical interaction ComPPI
EEF2 FARSA 25348397 N/A physical interaction ComPPI
XRCC3 FARSA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAN2 FARSA 25348397 N/A physical interaction ComPPI
RRP1B FARSA 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
COG4 FARSA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
A2M FARSA 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CYLD FARSA 25348397 N/A physical interaction ComPPI
OFD1 FARSA 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF32 FARSA 25348397 N/A physical interaction ComPPI
PSMG2 FARSA 25348397 N/A physical interaction ComPPI
FBXO6 FARSA 25348397 N/A physical interaction ComPPI
TARS1 FARSA 25348397 N/A physical interaction ComPPI
IRF2BP1 FARSA 25348397 N/A physical interaction ComPPI
ASB4 FARSA 25348397 N/A physical interaction ComPPI
ECPAS FARSA 25348397 N/A physical interaction ComPPI
OTUB1 FARSA 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
TDGF1P3 FARSA 25348397 N/A physical interaction ComPPI
RPLP0P6 FARSA 25348397 N/A physical interaction ComPPI
RIPK4 FARSA 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
CCT6B FARSA 25348397 N/A physical interaction ComPPI
USP32 FARSA 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FARSA UNC93B1 25348397 N/A physical interaction ComPPI
FARSA FARSB 20223217 22939629 24234451 25348397 26186194 26344197 27898060 physical association two hybrid,molecular sieving,pull down,x-ray crystallography,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct,OmniPath
FARSA GORAB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FARSA PUS1 25348397 N/A physical interaction ComPPI
FARSA RC3H1 25348397 N/A physical interaction ComPPI
FARSA ZNF746 25348397 N/A physical interaction ComPPI
FARSA SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
FARSA LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
FARSA NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct

Visualization