Gene Information gene info

GENE:FGD6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FGD6
FullNmae FYVE, RhoGEF and PH domain containing 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21740
EnsembleID ENSG00000180263
Uniprot Q6ZV73

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FGD6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FGD6 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FGD6 cuproptosis 37243753 However, there are very few studies of cuproptosis in GC. In this paper, a prediction model related to cuproptosis was established and verified through data mining, and the six genes related to cuproptosis were ACLY, FGD6, SERPINE1, SPATA13, RANGAP1, and ADGRE5. genes related to cuproptosis

Go Annotation:

GeneSymbol Go id
FGD6 GO:0001726,GO:0005085,GO:0005737,GO:0005737,GO:0005794,GO:0005856,GO:0007010,GO:0008360,GO:0030027,GO:0030036,GO:0031267,GO:0043087,GO:0046847,GO:0046872

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR FGD6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 FGD6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FGD6 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FGD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FGD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FGD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FGD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FGD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FGD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FGD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FGD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 FGD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 FGD6 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 FGD6 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000001C659 FGD6 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F FGD6 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 FGD6 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A FGD6 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 FGD6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004AD450 FGD6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 FGD6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 FGD6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 FGD6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 FGD6 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000358C16 FGD6 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NPM1 FGD6 25348397 N/A physical interaction ComPPI
YWHAG FGD6 14525934 15324660 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CBY1 FGD6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GRB2 FGD6 21706016 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDGFRB FGD6 25348397 N/A physical interaction ComPPI
DBNL FGD6 25348397 N/A physical interaction ComPPI
CTR9 FGD6 25348397 N/A physical interaction ComPPI
TRIM25 FGD6 25348397 N/A physical interaction ComPPI
ACVR1 FGD6 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CGN FGD6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF13B FGD6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PLK2 FGD6 25348397 N/A physical interaction ComPPI
FGD6 CCDC102B 25348397 N/A physical interaction ComPPI
FGD6 KSR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
H2BC9 FGD6 24234451 30021884 physical association cross-linking study IntAct

Visualization