GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
FGD6
FullNmae
FYVE, RhoGEF and PH domain containing 6
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:21740
EnsembleID
ENSG00000180263
Uniprot
Q6ZV73
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
FGD6
immunogenic
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
FGD6
autosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
FGD6
cuproptosis
37243753
However, there are very few studies of cuproptosis in GC. In this paper, a prediction model related to cuproptosis was established and verified through data mining, and the six genes related to cuproptosis were ACLY, FGD6, SERPINE1, SPATA13, RANGAP1, and ADGRE5.
genes related to cuproptosis
Go Annotation:
GeneSymbol
Go id
FGD6
GO:0001726,GO:0005085,GO:0005737,GO:0005737,GO:0005794,GO:0005856,GO:0007010,GO:0008360,GO:0030027,GO:0030036,GO:0031267,GO:0043087,GO:0046847,GO:0046872
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
AR
FGD6
20610535
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
GATA1
FGD6
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
GATA2
FGD6
18971253
19941826
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
FGD6
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
FGD6
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
FGD6
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
FGD6
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
FGD6
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
FGD6
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
FGD6
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
MITF
FGD6
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
SPI1
FGD6
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000237AF9
FGD6
18185580
25416803
mrna cleavage,inhibition
array technology
TarBase
URS0000122ED0
FGD6
19088304
25416803
mrna cleavage,inhibition
array technology
TarBase
URS000001C659
FGD6
20371350
23446348
25416803
mrna cleavage,inhibition
clip
TarBase
URS000021202F
FGD6
20371350
23446348
25416803
mrna cleavage,inhibition
clip
TarBase
URS000021D7C8
FGD6
20371350
23446348
25416803
mrna cleavage,inhibition
clip
TarBase
URS000016FD1A
FGD6
23446348
25416803
mrna cleavage,inhibition
clip
TarBase
URS00005586D0
FGD6
22012620
25416803
mrna cleavage,inhibition
clip
TarBase
URS00004AD450
FGD6
22012620
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000122F23
FGD6
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000008A99
FGD6
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000075B538
FGD6
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003BD367
FGD6
19536157
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000358C16
FGD6
19536157
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
NPM1
FGD6
25348397
N/A
physical interaction
ComPPI
YWHAG
FGD6
14525934
15324660
25348397
N/A
experimental interaction detection,in vivo
ComPPI,HPRD
CBY1
FGD6
24234451
25348397
physical association
physical interaction,inference by socio-affinity scoring
ComPPI,IntAct
GRB2
FGD6
21706016
24234451
25348397
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
PDGFRB
FGD6
25348397
N/A
physical interaction
ComPPI
DBNL
FGD6
25348397
N/A
physical interaction
ComPPI
CTR9
FGD6
25348397
N/A
physical interaction
ComPPI
TRIM25
FGD6
25348397
N/A
physical interaction
ComPPI
ACVR1
FGD6
14525934
15761153
25348397
N/A
experimental interaction detection,in vivo
ComPPI,HPRD
CGN
FGD6
24234451
25348397
physical association
physical interaction,inference by socio-affinity scoring
ComPPI,IntAct
KIF13B
FGD6
24234451
25348397
physical association
physical interaction,inference by socio-affinity scoring
ComPPI,IntAct
PLK2
FGD6
25348397
N/A
physical interaction
ComPPI
FGD6
CCDC102B
25348397
N/A
physical interaction
ComPPI
FGD6
KSR1
24234451
25348397
physical association
physical interaction,inference by socio-affinity scoring
ComPPI,IntAct
H2BC9
FGD6
24234451
30021884
physical association
cross-linking study
IntAct
Visualization