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GENE：FNTA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FNTA
FullNmae farnesyltransferase, CAAX box, subunit alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3782
EnsembleID ENSG00000168522
Uniprot P49354

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FNTA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FNTA autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FNTA GO:0004660,GO:0004660,GO:0004661,GO:0004662,GO:0004663,GO:0005515,GO:0005737,GO:0005829,GO:0005875,GO:0005886,GO:0005953,GO:0005953,GO:0005965,GO:0005965,GO:0007179,GO:0008017,GO:0018343,GO:0018343,GO:0018344,GO:0018344,GO:0030548,GO:0030971,GO:0043014,GO:0045213,GO:0060090,GO:0071340,GO:0090044,GO:0090045

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FNTA hsa:2339 path:hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 FNTA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR FNTA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
RHOA FNTA 25361965 interaction type N/A PTMCode2
FNTA RHOA 25361965 interaction type N/A PTMCode2
HRAS FNTA 25361965 interaction type N/A PTMCode2
FNTA HRAS 25361965 interaction type N/A PTMCode2
FNTA PGGT1B 25361965 interaction type N/A PTMCode2
PGGT1B FNTA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRAS FNTA 12374986 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HK2 FNTA 25348397 N/A physical interaction ComPPI
TGFB1 FNTA 14525934 25348397 8599089 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
HEYL FNTA 25348397 N/A physical interaction ComPPI
HRAS FNTA 14525934 2217184 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
VAV2 FNTA 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PGGT1B FNTA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RHOB FNTA 1400319 14525934 25348397 7713879 N/A experimental interaction detection,in vitro ComPPI,HPRD
TGM2 FNTA 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
STAT2 FNTA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTP4A2 FNTA 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAP2A FNTA 15451670 24234451 25348397 physical association x-ray crystallography ComPPI,IntAct
HDAC6 FNTA 25348397 N/A physical interaction ComPPI
CENPF FNTA 10852915 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ACVR1 FNTA 14525934 25348397 8599089 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FNTA FNTB 11687658 12036349 12825937 14525934 15170324 15248757 15451670 24234451 25348397 27898060 physical association experimental interaction detection,x-ray crystallography,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct,OmniPath
FNTA GBP1 10676968 11598000 14525934 25348397 8830800 N/A experimental interaction detection,in vitro ComPPI,HPRD
FNTA PTP4A3 10747914 14525934 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
FNTA TGFBR1 14525934 25348397 8530343 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
FNTA INHBB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FNTA SAFB2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FNTA RPL13A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FNTA DYRK1A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
FNTA AMMECR1L 25348397 N/A physical interaction ComPPI
FNTA NAP1L1 25348397 N/A physical interaction ComPPI
FNTA DARS2 25348397 N/A physical interaction ComPPI
FNTA CAPN1 25348397 N/A physical interaction ComPPI
FNTA ARFGAP1 25348397 N/A physical interaction ComPPI
FNTA TSKS 25348397 N/A physical interaction ComPPI
FNTA RPL18 25348397 N/A physical interaction ComPPI
FNTA CEFIP 25348397 N/A physical interaction ComPPI
FNTA EPB41L5 25348397 N/A physical interaction ComPPI
FNTA FAM117B 25348397 N/A physical interaction ComPPI
FNTA ARNT2 25348397 N/A physical interaction ComPPI
AP4M1 FNTA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FNTA HRAS 2217184 24294527 27898060 stimulant N/A OmniPath
FNTA KRAS 12374986 24294527 27898060 stimulant N/A OmniPath
FNTA MRAS 24294527 27898060 stimulant N/A OmniPath

Visualization










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