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GENE：FNTB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FNTB
FullNmae farnesyltransferase, CAAX box, subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3785
EnsembleID ENSG00000257365
Uniprot P49356

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FNTB autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FNTB GO:0004660,GO:0004660,GO:0005515,GO:0005829,GO:0005875,GO:0005965,GO:0005965,GO:0006629,GO:0008270,GO:0018343,GO:0018343

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FNTB hsa:2342 path:hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR FNTB 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F6 FNTB 12909625 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 FNTB 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 FNTB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FNTB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A FNTB 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink

Source Target Pmid Interactiontype Methods Database
URS0000134ADC FNTB 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS0000345DEB FNTB 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
KRAS FNTB 12374986 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ATPAF2 FNTB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GLYR1 FNTB 25348397 N/A physical interaction ComPPI
HRAS FNTB 14525934 15451670 2217184 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
AVP FNTB 25348397 N/A physical interaction ComPPI
RRAS2 FNTB 14525934 15451670 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
UBB FNTB 25348397 N/A physical interaction ComPPI
RAP2A FNTB 14525934 15451670 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HDAC6 FNTB 25348397 N/A physical interaction ComPPI
CYFIP1 FNTB 25348397 N/A physical interaction ComPPI
PPM1B FNTB 25348397 N/A physical interaction ComPPI
CENPF FNTB 10852915 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CAST FNTB 25348397 N/A physical interaction ComPPI
FNTA FNTB 11687658 12036349 12825937 14525934 15170324 15248757 15451670 24234451 25348397 27898060 physical association experimental interaction detection,x-ray crystallography,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct,OmniPath
ARFGAP1 FNTB 25348397 N/A physical interaction ComPPI
PTP4A1 FNTB 25348397 N/A physical interaction ComPPI
CAPNS1 FNTB 25348397 N/A physical interaction ComPPI
CAPN1 FNTB 25348397 N/A physical interaction ComPPI
AURKAIP1 FNTB 25348397 N/A physical interaction ComPPI
TROAP FNTB 25348397 N/A physical interaction ComPPI
DCAF7 FNTB 25348397 N/A physical interaction ComPPI
DYRK1A FNTB 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NPLOC4 FNTB 25348397 N/A physical interaction ComPPI
ARNT2 FNTB 25348397 N/A physical interaction ComPPI
YKT6 FNTB 25348397 N/A physical interaction ComPPI
AGXT FNTB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRPSAP2 FNTB 25348397 N/A physical interaction ComPPI
SPDL1 FNTB 25348397 N/A physical interaction ComPPI
GRIP1 FNTB 25348397 N/A physical interaction ComPPI
FNTB PTP4A3 10747914 14525934 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
FNTB HOOK3 25348397 N/A physical interaction ComPPI
FNTB LMNB2 25348397 N/A physical interaction ComPPI
FNTB RPL18 25348397 N/A physical interaction ComPPI
FNTB MRPS11 25348397 N/A physical interaction ComPPI
FNTB HOXC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FNTB SMG9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GBP1 FNTB 10676968 11598000 14525934 25348397 8830800 N/A experimental interaction detection,in vitro ComPPI,HPRD
FNTB HRAS 15451670 2217184 24294527 27898060 stimulant N/A OmniPath
FNTB KRAS 12374986 24294527 27898060 stimulant N/A OmniPath
FNTB MRAS 24294527 27898060 stimulant N/A OmniPath

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