GENE：GPATCH8
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GPATCH8 |
| FullNmae | G-patch domain containing 8 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29066 |
| EnsembleID | ENSG00000186566 |
| Uniprot | Q9UKJ3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GPATCH8 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GPATCH8 | GO:0003723,GO:0005515,GO:0005575,GO:0005634,GO:0008150,GO:0046872 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | GPATCH8 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | GPATCH8 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | GPATCH8 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | GPATCH8 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | GPATCH8 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | GPATCH8 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | GPATCH8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | GPATCH8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | GPATCH8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | GPATCH8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | GPATCH8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | GPATCH8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | GPATCH8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | GPATCH8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | GPATCH8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000272039 | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00002C0FCB | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00003BBF48 | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS000027080C | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005E1A16 | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019F055 | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000610EFA | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000140295 | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000214763 | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000047A8F | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A611 | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | GPATCH8 | 20371350 22473208 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | GPATCH8 | 20371350 22473208 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | GPATCH8 | 20371350 22473208 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012A1DD | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171525 | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000055BBE5 | GPATCH8 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D50C | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003804D8 | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A6D0C | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E1509 | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E628F | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CBE63 | GPATCH8 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005E6F45 | GPATCH8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FF522 | GPATCH8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000013D17D | GPATCH8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | GPATCH8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B7E30 | GPATCH8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CD2BP2 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| ATXN1 | GPATCH8 | 14525934 16713569 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| BMI1 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| SNIP1 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| EGLN3 | GPATCH8 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| U2AF2 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| BTRC | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| CLK2 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| EWSR1 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| EPB41L3 | GPATCH8 | 24234451 24366813 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| EPB41L2 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| EGFR | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| JAK3 | GPATCH8 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HIF1AN | GPATCH8 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| TRIM25 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| APH1A | GPATCH8 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| RBFOX2 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| TERF2 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| CLK3 | GPATCH8 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| RNPS1 | GPATCH8 | 17353931 24234451 25348397 26496610 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NUMBL | GPATCH8 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| LUC7L | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| LUC7L2 | GPATCH8 | 25348397 | N/A | physical interaction | ComPPI |
| GPATCH8 | TP53 | 25348397 | N/A | physical interaction | ComPPI |
| GPATCH8 | FDX1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GPATCH8 | PON2 | 25348397 | N/A | physical interaction | ComPPI |
| GPATCH8 | PCGF1 | 25348397 | N/A | physical interaction | ComPPI |
| GPATCH8 | NANOG | 25348397 | N/A | physical interaction | ComPPI |
| GPATCH8 | PIP4K2A | 25348397 | N/A | physical interaction | ComPPI |
| GPATCH8 | ESRP1 | 25348397 | N/A | physical interaction | ComPPI |
| H1-5 | GPATCH8 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| H2BC9 | GPATCH8 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| H2AX | GPATCH8 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| H1-4 | GPATCH8 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| HNRNPD | GPATCH8 | 24234451 30021884 | physical association | cross-linking study | IntAct |