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GENE：AGFG1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AGFG1
FullNmae ArfGAP with FG repeats 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5175
EnsembleID ENSG00000173744
Uniprot P52594

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AGFG1 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AGFG1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AGFG1 GO:0001675,GO:0003677,GO:0003723,GO:0005096,GO:0005515,GO:0005643,GO:0005737,GO:0005829,GO:0006406,GO:0007289,GO:0031410,GO:0043231,GO:0045109,GO:0046872

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 AGFG1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 AGFG1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 AGFG1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 AGFG1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 AGFG1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 AGFG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 AGFG1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000035CC3E AGFG1 20371350 21572407 23446348 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00000A057E AGFG1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 AGFG1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 AGFG1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 AGFG1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 AGFG1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 AGFG1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B AGFG1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EPS15 AGFG1 25361965 interaction type N/A PTMCode2
AGFG1 EPS15 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SH3GLB1 AGFG1 25348397 N/A physical interaction ComPPI
HSPBP1 AGFG1 25348397 N/A physical interaction ComPPI
RDH12 AGFG1 25348397 N/A physical interaction ComPPI
P3H1 AGFG1 25348397 N/A physical interaction ComPPI
APC AGFG1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CDH1 AGFG1 25348397 N/A physical interaction ComPPI
PKIA AGFG1 14525934 25348397 27898060 8805303 N/A two hybrid,two hybrid ComPPI,HPRD,OmniPath
DBNL AGFG1 25348397 N/A physical interaction ComPPI
XPO1 AGFG1 14525934 25348397 27898060 9368759 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
IPO11 AGFG1 25348397 N/A physical interaction ComPPI
EPS15 AGFG1 10613896 11062555 14525934 24234451 25348397 27898060 9303539 9446614 9721102 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
ITSN1 AGFG1 25348397 N/A physical interaction ComPPI
VAMP7 AGFG1 14525934 18775314 24234451 25348397 physical association two hybrid,experimental interaction detection,isothermal titration calorimetry,pull down,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
OGT AGFG1 25348397 N/A physical interaction ComPPI
VCAM1 AGFG1 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 AGFG1 25348397 N/A physical interaction ComPPI
GPN1 AGFG1 25348397 N/A physical interaction ComPPI
LPP AGFG1 25348397 N/A physical interaction ComPPI
SUCLA2 AGFG1 25348397 N/A physical interaction ComPPI
TRIM25 AGFG1 25348397 N/A physical interaction ComPPI
MPP1 AGFG1 25348397 N/A physical interaction ComPPI
AGFG1 EPS15L1 10613896 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
AGFG1 RNF216 11854271 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
AGFG1 APP 25348397 N/A physical interaction ComPPI
AGFG1 ALAD 25348397 N/A physical interaction ComPPI
AGFG1 ARPC1A 25348397 N/A physical interaction ComPPI
AGFG1 LAP3 25348397 N/A physical interaction ComPPI
AGFG1 NIF3L1 25348397 N/A physical interaction ComPPI
AGFG1 PPME1 25348397 N/A physical interaction ComPPI
AGFG1 SURF2 25348397 N/A physical interaction ComPPI
AGFG1 TPRKB 25348397 N/A physical interaction ComPPI
AGFG1 ZPR1 25348397 N/A physical interaction ComPPI
AGFG1 POLE2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AGFG1 NYAP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AGFG1 FCGR2A 25348397 N/A physical interaction ComPPI
AGFG1 FSD1 25348397 N/A physical interaction ComPPI
AGFG1 CEP170 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
AGFG1 ESR1 25348397 N/A physical interaction ComPPI
AGFG1 AGFG2 25348397 N/A physical interaction ComPPI
AGFG1 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AGFG1 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AGFG1 MFHAS1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
AGFG1 AGFG1 11854271 14525934 N/A experimental interaction detection HPRD
AGFG1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
TNFRSF1A AGFG1 10358032 10755617 10795740 11002422 11734559 12167698 12721308 16611992 18641653 18939944 19524513 20547836 27898060 8612133 8642271 9082980 9714541 N/A N/A OmniPath
TNFRSF10A AGFG1 10958661 27898060 9430227 N/A N/A OmniPath

Visualization










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