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GENE：KPNA5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KPNA5
FullNmae karyopherin subunit alpha 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6398
EnsembleID ENSG00000196911
Uniprot O15131

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KPNA5 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KPNA5 GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005654,GO:0005829,GO:0005829,GO:0005829,GO:0006606,GO:0006607,GO:0008139,GO:0042564,GO:0061608

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KPNA5 hsa:3841 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)
KPNA5 hsa:3841 path:hsa05164 Influenza A - Homo sapiens (human)
KPNA5 hsa:3841 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR KPNA5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 KPNA5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 KPNA5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KPNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KPNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KPNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 KPNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 KPNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 KPNA5 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000A07C1 KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000338542 KPNA5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 KPNA5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000041E11D KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 KPNA5 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 KPNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E KPNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B KPNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000512C88 KPNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E KPNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000498DAA KPNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AD450 KPNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 KPNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B KPNA5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 KPNA5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A KPNA5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA KPNA5 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GATAD2B KPNA5 25348397 N/A physical interaction ComPPI
KPNA5 ANP32A 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
KPNA5 CDKN1B 14525934 15057270 22770219 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,biochemical,in vitro ComPPI,HPRD,IntAct
KPNA5 BRMS1 16919237 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KPNA5 MEPCE 25348397 N/A physical interaction ComPPI
KPNA5 CHD4 25348397 N/A physical interaction ComPPI
KPNA5 CUL3 25348397 N/A physical interaction ComPPI
KPNA5 KPNB1 25348397 N/A physical interaction ComPPI
KPNA5 IL32 25348397 N/A physical interaction ComPPI
KPNA5 NUP50 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KPNA5 MOV10 25348397 N/A physical interaction ComPPI
KPNA5 NXF1 25348397 N/A physical interaction ComPPI
KPNA5 ZRANB2 25348397 N/A physical interaction ComPPI
KPNA5 FBL 25348397 N/A physical interaction ComPPI
KPNA5 IPO5 25348397 N/A physical interaction ComPPI
KPNA5 RAN 25348397 N/A physical interaction ComPPI
KPNA5 RPS8 25348397 N/A physical interaction ComPPI
KPNA5 MCM2 25348397 N/A physical interaction ComPPI
KPNA5 RBBP4 25348397 N/A physical interaction ComPPI
KPNA5 TWIST1 25348397 N/A physical interaction ComPPI
KPNA5 PHB2 25348397 N/A physical interaction ComPPI
KPNA5 RNMT 25348397 N/A physical interaction ComPPI
KPNA5 PTPN2 25348397 N/A physical interaction ComPPI
KPNA5 WT1 25348397 N/A physical interaction ComPPI
KPNA5 AICDA 19412186 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
KPNA5 SKP2 22770219 24234451 25348397 physical association pull down ComPPI,IntAct
KPNA5 TRIP12 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
KPNA5 SF1 24234451 25348397 26420826 physical association two hybrid fragment pooling approach ComPPI,IntAct
KPNA5 LMNA 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KPNA5 H3C1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KPNA5 LARP7 18281698 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ANP32B KPNA5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

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