Gene Information gene info

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GENE：LYST

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LYST
FullNmae lysosomal trafficking regulator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1968
EnsembleID ENSG00000143669
Uniprot Q99698

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LYST lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LYST autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LYST GO:0005515,GO:0005829,GO:0006909,GO:0008104,GO:0015031,GO:0015630,GO:0016020,GO:0019901,GO:0030595,GO:0032438,GO:0032510,GO:0033364,GO:0042267,GO:0042742,GO:0042832,GO:0043473,GO:0051607

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR LYST 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LYST 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 LYST 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 LYST 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 LYST 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 LYST 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000DDD35 LYST 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001A7F58 LYST 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000367985 LYST 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
TNNI3 LYST 25348397 N/A physical interaction ComPPI
HNRNPH2 LYST 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KPNB1 LYST 11984006 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
DAP3 LYST 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAB LYST 11984006 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
YWHAZ LYST 25348397 N/A physical interaction ComPPI
HGS LYST 11984006 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
YWHAQ LYST 11984006 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
CENPJ LYST 25348397 N/A physical interaction ComPPI
MED12 LYST 11984006 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
LYST ESRRA 11984006 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
LYST MRPL17 11984006 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
LYST NCDN 11984006 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
LYST CNTROB 11984006 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
LYST CSNK2B 11984006 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
LYST HNRNPM 11984006 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
LYST MRPS31 25348397 N/A physical interaction ComPPI
LYST ATN1 11984006 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
LYST EFS 25348397 N/A physical interaction ComPPI
LYST ZNF521 25348397 N/A physical interaction ComPPI
LYST LLGL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LYST MLH1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LYST PPIA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LYST TACC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LYST SAP30 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LYST GAR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LYST KLC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LYST CALM2 11984006 14525934 N/A experimental interaction detection,two hybrid HPRD

Source Target Pmid Interactiontype Methods Database
URS00008BDE52 LYST 27087310 direct interaction,inhibition N/A NPInter

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