Gene Information gene info

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GENE：MED17

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MED17
FullNmae mediator complex subunit 17
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2375
EnsembleID ENSG00000042429
Uniprot Q9NVC6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MED17 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MED17 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MED17 GO:0000151,GO:0003712,GO:0003712,GO:0003713,GO:0005515,GO:0005634,GO:0005654,GO:0005667,GO:0006357,GO:0006357,GO:0006367,GO:0016020,GO:0016567,GO:0016592,GO:0016592,GO:0030374,GO:0030374,GO:0032968,GO:0035019,GO:0042809,GO:0045893,GO:0045944,GO:0046966,GO:0051123,GO:0060261,GO:0060261,GO:0061630,GO:0070847,GO:0070847

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MED17 hsa:9440 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MED17 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 MED17 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MED17 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MED17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MED17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MED17 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F2 MED17 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002367FA MED17 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA MED17 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F MED17 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 MED17 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 MED17 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 MED17 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 MED17 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA MED17 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A MED17 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E MED17 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 MED17 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B MED17 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 MED17 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 MED17 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MED17 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 MED17 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 MED17 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 MED17 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 MED17 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 MED17 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TP53BP1 MED17 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
MED21 MED17 25348397 N/A physical interaction ComPPI
MED8 MED17 14525934 14576168 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
EMC2 MED17 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXW7 MED17 25348397 N/A physical interaction ComPPI
TRIP4 MED17 25348397 N/A physical interaction ComPPI
GATA1 MED17 17132730 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
THRA MED17 14576168 24234451 25348397 association pull down ComPPI,IntAct
MED1 MED17 20098423 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PPARGC1A MED17 25348397 N/A physical interaction ComPPI
MED24 MED17 25348397 N/A physical interaction ComPPI
NTRK1 MED17 25348397 N/A physical interaction ComPPI
NR1I3 MED17 25348397 N/A physical interaction ComPPI
PARP1 MED17 25348397 N/A physical interaction ComPPI
SMARCA4 MED17 25348397 N/A physical interaction ComPPI
SREBF1 MED17 25348397 N/A physical interaction ComPPI
LMO2 MED17 25348397 N/A physical interaction ComPPI
CTDP1 MED17 25348397 N/A physical interaction ComPPI
MED30 MED17 12584197 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MED9 MED17 14638676 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED23 MED17 25348397 N/A physical interaction ComPPI
TRRAP MED17 25348397 N/A physical interaction ComPPI
CDK7 MED17 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KAT2A MED17 18418385 24234451 25348397 association physical interaction,biochemical ComPPI,IntAct
HNF4A MED17 25348397 N/A physical interaction ComPPI
MED17 USP49 14525934 14576168 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MED17 MED19 14576168 14638676 15175163 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,in vitro ComPPI,IntAct
MED17 BRCA1 25348397 N/A physical interaction ComPPI
MED17 MED10 12149480 12584197 14576168 14638676 15175163 17404243 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED17 BARD1 25348397 N/A physical interaction ComPPI
MED17 CDK8 20098423 23602568 24234451 25348397 26496610 29568061 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
MED17 TP53 10198638 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
MED17 ESR2 21182203 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
MED17 ESR1 21182203 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
MED17 BRD4 25348397 N/A physical interaction ComPPI
MED17 RPAP2 25348397 N/A physical interaction ComPPI
MED17 GPN1 25348397 N/A physical interaction ComPPI
MED17 MED12 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED17 ZC3H13 25348397 N/A physical interaction ComPPI
MED17 QKI 25348397 N/A physical interaction ComPPI
MED17 MED14 25348397 N/A physical interaction ComPPI
MED17 BCL6 25348397 N/A physical interaction ComPPI
MED17 SUZ12 25348397 N/A physical interaction ComPPI
MED17 TFIP11 25348397 N/A physical interaction ComPPI
MED17 CPSF2 25348397 N/A physical interaction ComPPI
MED17 WDR33 25348397 N/A physical interaction ComPPI
MED17 EPAS1 25348397 N/A physical interaction ComPPI
MED17 POLR2C 18562274 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED17 CDK19 15175163 23602568 24234451 25348397 association,physical association physical interaction,ion exchange chromatography,tandem affinity purification ComPPI,IntAct
MED17 CCNC 25348397 N/A physical interaction ComPPI
MED17 POLR2G 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED17 TCL1B 25348397 N/A physical interaction ComPPI
MED17 MED13 25348397 N/A physical interaction ComPPI
MED17 MED20 25348397 N/A physical interaction ComPPI
MED17 MED4 25348397 N/A physical interaction ComPPI
MED17 FOS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED17 XRCC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED17 EXOSC4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED17 TENT4B 25348397 N/A physical interaction ComPPI
MED17 HEMGN 25348397 N/A physical interaction ComPPI
MED17 BIRC5 25348397 N/A physical interaction ComPPI
MED17 TKT 25348397 N/A physical interaction ComPPI
MED28 MED17 24234451 24882805 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED18 MED17 24234451 24882805 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED17 ARM 12021283 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
MED17 N 12021283 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct

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